BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 1 Biomedical Imaging 2 Class 9 – Electric and Magnetic Field Imaging: Electroencephalography (EEG), Magnetoencephalography.

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Presentation transcript:

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 1 Biomedical Imaging 2 Class 9 – Electric and Magnetic Field Imaging: Electroencephalography (EEG), Magnetoencephalography (MEG). Part 1: Theory 04/02/08

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 2 Biological Contrast Mechanisms Electric stimulation with electric field Electrotherapy Electric stimulation with magnetic field Magnetoelectrotherapy Magnetization of material Magnetotherapy Electric field from electric sources Magnetic field from bioelectric sources Magnetic field from magnetic material Electric measurement of electric impedance Magnetic measurement of electric impedance Magnetic measurement of magnetic susceptibility

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 3 Microscopic Ion Concentrations Membrane

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 4 Simplified Membrane, Ion Channel Depiction

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 5 Microscopic Ion Currents Membrane

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 6 Propagation of Ion Currents

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 7 Propagation of Ion Currents

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 8 Typical Voltage vs. Time Transients

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 9 Interaction of Nerve and Muscle

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 10 Electromyography (EMG)

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 11 Examples of EMG Recordings

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 12 Electrocardiography (ECG, EKG)

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 13 Electrocardiography (ECG, EKG)

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 14 Magnetocardiography (MCG)

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 15 Magnetocardiography (MCG)

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 16 Electric Transmission of Biological Information

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 17 Electric Transmission of Biological Information

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 18 Invasive Recording of Electric Activity

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 19 Properties of Electrically Active Tissues

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 20 “Typical” Central Nervous System (CNS) Neuron

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 21 Microscopic/Internal → Macroscopic/External

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 22 EEG and MEG Have Different Surface Effects

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 23 EEG and MEG Have Different Surface Effects

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 24 EEG and MEG Have Different Surface Effects

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 25 EEG and MEG Have Different Surface Effects

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 26 Typical Event-Related Potential (ERP) Measurement

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 27 Averaging Across Repeats (Time-Series Analysis!)

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 28 ERP Components

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 29 But Can We Do ERP Imaging?

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 30 Theoretical Advantages of MEG

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 31 Spatial Resolution of MEG

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 32 Spatial Resolution of MEG

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 33 Comparison of Properties of Functional Brain Imaging Methods

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 34 Measurement Apparatus

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 35 Scale of Biomagnetic Fields

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 36 MEG Helmet

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 37 MEG Raw Data and Image

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 38 Placement of EEG Electrodes

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 39 Placement of EEG Electrodes

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 40 Dependence of Amplitude on Position

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 41 Spatial Sensitivity of an EEG Electrode Pair

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 42 EEG Waveforms—Frequency Bands

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 43 Power Spectrum of Typical EEG

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 44 Behavioral Correlates of EEG Waveforms

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 45 Locating Source of EEG Signal (e.g., Epileptic Focus)

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 46 Locating Source of EEG Signal (e.g., Epileptic Focus)

BMI2 SS08 – Class 9 “EEG-MEG 1” Slide 47 Locating Source of EEG Signal (e.g., Epileptic Focus)