H.Gaub / SS 2007BPZ§4.31 All pore-forming ion channels are similar in structure

H.Gaub / SS 2007BPZ§4.32 Struktur des K-Kanals Rod MacKinnon Chemie Nobelpreis 2003

H.Gaub / SS 2007BPZ§4.33 Crystal is defined and stabilized by Antibodies

H.Gaub / SS 2007BPZ§4.34 Chemistry of Ion Coordination and Hydration Revealed by a K+ Channel-Fab Complex at 2.0 Angstrom Resolution; MacKinnon, R., et al.; Nature, Vol. 414; January 1, 2001 Potassium Channel Receptor Site for the Inactivation Gate and Quaternary Amine Inhibitors; MacKinnon, R., et al.; Nature, Vol. 411; March 8, 2001 Energetic Optimization of Ion Conduction Rate by the K+ Selectivity Filter; MacKinnon, R., et al.; Nature, Vol. 414; November 1, 2001

H.Gaub / SS 2007BPZ§4.35 Ionenselektivität des Natriumkanals

H.Gaub / SS 2007BPZ§4.36

H.Gaub / SS 2007BPZ§4.37 Alternative Stacking of K+ (Green) and Water (red) High K+ Concentration (2M)

H.Gaub / SS 2007BPZ§4.38 Gating by conformational changes of the tetramer