Maintain quality of life through Modern Chinese Herbal Medicine Speaker : Dr.Joseph H.C.Lui Ph D. Pharmacognosy University of Minnesota, USA Registered Chinese Medicine Practitioner, Hong Kong.

Content  Unlock the mystery of Chinese herbal medicine  Why Chinese herbal medicine has to be modernized?  Maintain quality of life

Unlock the Mystery of Chinese Herbal Medicine

General Concept Chinese Medicine Minimum side effects Cure (treating the underlying illness) Natural Compound Formulation Western Drug Harmful side effects Control (alleviating the symptoms) Chemical Compound Single Component Formulation

Types of Chinese Medicine  5776 items (Pharmacopoeia of Chinese Herbal Medicine)  Animal, Plant, Microorganism, Mineral  All natural  Processed and Refined into Chinese Medicine  Modern Chinese herbal medicine

Types of Western Drug  1300 items (PDR)  Animal, Plant, Microorganism, Mineral, Synthetic, Biotechnology  > 50% natural  Extraction and purification

Chinese vs Western Drug  Compound Formulation  Single component Formulation

Make Up of Compound Formulation  Know-how  Art instead of Science  Experience and Clinical Studies  337 known formulae

Principal herb — Main ingredient for the cure Assistant herb — Strengthens the effect of the principal herb Adjuvant herb — Reduces or eliminates the toxicity and other side effects of the principal and the assistant herbs Guiding herb — Directs, Coordinates and/or mediates the effects of the principal and assistant herbs to the affected site

Bazhen Tang (Reinforcing the vital energy & nourishing the blood) Radix Codonopsis Pilosulae 10g Rhizoma Atractylodis Macrocephalae 10g Poria 10g Radix Glycyrrhizae 5g Rhizoma Ligustici Chuanxiong 10g Radix Angelicae Sinensis 10g Radix Paeoniae Alba 10g Rhizoma Rehmanniae Preparatae 10g A typical compound formula embodied Principle, Assistant, Adjuvant & Guiding herbs

Compound Formulation of Western Drug – Aids Treatment  Dr. David Ho is one of the well- known scientists in Aids research  Develop Cocktail Treatment

What is Cocktail Treatment  Mixing three to four kinds of antiviral drugs  Compound formulation  RITONAVIR + AZT + 3TC  INDINAVIR + AZT + 3TC

Why Cocktail Treatment is better ?  Virus being attacked in various mode of actions  Wide spectrum  Control but not cure

Adjuvant Drug  Reduce side effects  Bufferin  Aspirin – moderate pain and reduce fever  Sodium Bicarbonate – neutralize stomach acid Synergistic

Guiding Drug  Monoclonal Antibody  Targeting Drug  Magic Bullet Touch-and-go

The Advantages of Compound Formulation  Multi specificity vs high specificity  Wide spectrum  Synergistic  Multi channels  Same functions but with different mode of actions

Why Chinese Herbal Medicine has to be modernized ?

Principles of Modern Chinese Herbal Medicine  Safety  Efficacy  Stability & Consistency

Raw Materials Safety  Heavy metals  Microbes contamination  Herbacide & Insecticide Residues

Products Safety  Acute Toxicity Study  Subacute Toxicity Study  Chronic Toxicity Study  Reproductive Toxicology  Drug Dependence  Antigenicity Study  Mutagenicity Study  Carcinogenicity Study  Local Irritation Study Good Laboratory Practices

Efficacy  In-vitro Study  In-vivo Study  Animal study  Clinical study  Clinical Trial  Unbiased  Independent  Properly designed Good Clinical Practices

Stability & Consistency  Whole Plants Authentication Tissue Analysis Chemical Composition Analysis DNA Analysis  Manufacturing of Chinese Medicines Quality Control Quality Assurance Good Manufacturing Practices

No. 1  To prove the safety of herbal medicines  To provide strong scientific proof of the effectiveness of the herbal medicines through a well designed clinical trial  To strengthen batch to batch consistency which means quality assurance of the herbal medicines The genuine Modern Chinese Herbal Medicine

Maintain quality of life

Five Principle Elements for longevity  Blood pressure lower than 120/80  Total blood cholesterol lower than 200mg/dl  Normal blood sugar level  Free from smoking  Never have stroke According to the Journal of the American Medical Association 1999; 282: 2012 – 2018 *

People who meet the five principle elements for longevity ：  Average life-span will longer than normal person at least 9 1 / 2 years  Youngster < 9%  Middle-Age groups < 5%

Major reasons for aging  Inborn factor (40%)  Heredity  Acquired factor (60%)  Diseased factor (cardiac, liver, spleen, lung, kidney and cancer diseases)  Social factor (Science & culture, Substances & life style)  Environmental factor (Environmental pollution, viral or bacterial infection)  Other factor (Exercise, Eating habits, Mood, Health supplements)

Proper Lifestyle for Quality of Life  Proper exercise  Drink minimum 8 glasses of water everyday  Balanced diet  Eat lightly  Think positive  Proper health supplements

Good Health & Happy Life

Thank you ！