SERUM LEVELS OF IGF-1 IN FIRST EPISODE PSYCHOSIS AND CHRONIC SCHIZOPHRENIA PATIENTS COMPARED TO HEALTHY CONTROLS E. Ntouros 1, E. Karanikas 1, P. Ntafoulis.

Slides:

Advertisements

Similar presentations

Brain-morphological changes associated with acute antipsychotic treatment in first-episode schizophrenia Laila Asmal1, Bonginkosi Chiliza1, Stéfan du Plessis1,

Advertisements

Schizophrenia and Other Psychotic Disorders Anita S. Kablinger MD Associate Professor Departments of Psychiatry of Pharmacology LSUHSC-Shreveport.

Psychiatry interview History Taking

Social Cognition Moderates the Influence of Child Physical Abuse on Inpatient Psychiatric Rehabilitation Kee-Hong Choi, M.A. 1,2, Charlie A. Davidson,

Mood disorders ( affective disorders ) prof. MUDr. Eva Češková, CSc. Dept. of Psychiatry, Dept. of Psychiatry, Masaryk University, Brno Masaryk University,

Schizophrenia By: Khergtin Sanchez Period 4. Associated Features Schizophrenia- Mental disorder that is characterized by disorganized and delusional thinking,

Schizophrenia and Intellect Presentation by: Bryan Lang Caroline Helfrich and Jessica Wright Thomas W. Weickert, Terry E. Goldberg, James M. Gold, Llewellen.

CENTER FOR KOGNITIV TERAPI, SCT. HANS HOSPITAL

Page of 11 The Pennsylvania Child Welfare Training Program308: Adult Psychopathology: Bipolar Disorder 1 The Pennsylvania Child Welfare Training Program.

Réunion Ambulatoires SAS,  Similarly, a statistically significant MADRS reduction over time was found (F=156.2, p 800 mg/day) and low (

DEPRESSION Antonija Jukić Mentor: A. Žmegač Horvat.

The Changing Role of Medication in Advancing Recovery NYAPRS Conference.

By: Jerry & Nathan. Definition The bipolar disorder is when you have mood swings that range from the lows of depression to the highs of mania. These mood.

Schizophrenia Monica Gindi Table of Contents IntroductionSymptomsOnsetCause Neurological effect DiagnosisManagement.

Aripiprazole in the treatment of acute manic or mixed episodes in patients with bipolar I disorder:

Jouko Miettunen University of Oulu, Finland

Consultants: Jillian Lyon and Mary Ehlers The Impact of Atypical Antipsychotic Use on Obstructive Sleep Apnea.

David Rosenhan: Pseudo-Patient Experiment Investigated reliability of psychiatric diagnoses Eight healthy people entered psychiatric hospitals complaining.

Capacity Building: Iran Experience of Family Psychoeducation Yasaman Mottaghipour, Ph.D.

What is psychosis? D B Double

INTRODUCTION Dysregulation of Hypothalamic-Pituitary-Adrenal, (HPA), axis has been hypothesized to participate in the emergence of psychosis, yet findings.

THE IMPACT OF MARIJUANA ON HEALTH AND HEALTHCARE Ewald Horwath, MD, MS, FAPA Professor and Chair, Department of Psychiatry Associate Clinical Director,

INTRODUCTION During last decades much evidence has been accumulated concerning the neuroendocrine aetiopathological basis of schizophrenia. Recently research.

Goldstein (1988) Gottesman & Shields (1966)

Recognizing depression : specific issues among the female gender

EVIDENCE FOR ABERRANT TH1 AND TH2 IMMUNE RESPONSE IN DRUG NAÏVE FIRST EPISODE PSYCHOSIS E. Karanikas, E. Ntouros, D. Nasioudis, T. Valamoutopoulos, D.Balaskas,

PROFESSIONAL ACTIVITY AND SCHIZOPHRENIA: ASSOCIATED FACTORS AND IMPACT IN PROGNOSIS OUERFELLI I., JOMLI R., OUERTANI A., NACEF F. DEPARTMENT OF PSYCHIATRY.

INTRODUCTION The stress diathesis hypothesis of psychosis is one of the most prevailing models of the aetiopathology of psychotic disorders. Cortisol is.

Mental Disorders Mental Disorder- Is an illness that affects the mind and reduces person’s ability to function, adjust to change, or get along with others.

Sleep disturbance and suicidal intent in recent attempters P. Ferentinos 1, C. Christodoulou 1, E. Porichi 1, D. Dikeos 2, C. Papageorgiou 1 1 Athens University.

INCREASED CIRCULATING SERUM LEVELS OF MMP-9 AND VEGF-A ARE ASSOCIATED WITH OXIDATIVE STRESS IN PATIENTS WITH PRIMARY GLOMERULONEPHRITIS AND EARLY STAGES.

Diagnosing Mental Disorders- The Multiaxial Approach

Differential Diagnosis Schizoaffective Disorder Schizophrenia Schizophreniform Disorder Major Depressive Disorder (single episode), with mood-incongruent.

PATTERNS OF PSYCHOTROPIC DRUG PRESCRIPTION BEFORE AND AFTER EVALUATION IN A SPECIALIZED OUTPATIENT PROGRAM FOR BIPOLAR DISORDERS G.Michalopoulos, J-M.

ASSOCIATION OF CIRCULATING SERUM LEVELS OF VASCULAR ENDOTHELIAL GROWTH FACTOR-A WITH VASCULAR ULTRASOUND DETERMINANTS OF DEMENTIA IN PATIENTS WITH TYPE.

Schizophrenia Terrence Gault.

LENGTH OF FIRST HOSPITALIZATION AND OTHER PREDICTORS FOR RE-HOSPITALIZATION IN PSYCHOSES Jouko Miettunen, PhD Department of Psychiatry University of Oulu,

ASSOCIATION OF HYPOVITAMINAEMIA D AND TRANSFORMING GROWTH FACTOR – β1 IN THE PROGRESSION OF CHRONIC KIDNEY DISEASE Grigorios G. Dimas 1, Ilias E. Kanellos.

Barbara Pajk, M.N. University Psychiatric Clinic Ljubljana Barcelona,

OLD AGE PSYCHIATRY FOR PRIMARY CARE VOCATIONAL TRAINEES Dr Nick Pearson Consultant in the Psychiatry of Old Age Reading

Ron Beasley, PharmD Candidate Preceptor: Soheyla Mahdavian, PharmD

1 IRIS Initiative to Reduce the Impact of Schizophrenia DON’T DELAY! IT’S TIME TO REDUCE THE IMPACT OF PSYCHOSIS IN YOUNG PEOPLE……. NOW!

Going back to work or to study after a first-episode psychosis : the impact of an early intervention program over 5 years Amal Abdel-Baki (1,2), Geneviève.

SERUM LEVELS OF TISSUE INHIBITOR OF METALLOPROTEINASE-2 AND OX-LDL ARE ASSOCIATED WITH ATHEROSCLEROSIS IN PATIENTS WITH CΗRONIC KIDNEY DISEASE Grigorios.

Schizoaffective Disorder in Life

FIBROBLAST GROWTH FACTOR-23 AND HYPOVITAMINAEMIA D IN ANAEMIA OF TYPE 2 DIABETIC NEPHROPATHY Grigorios G. Dimas 1, Fotios S. Iliadis 1, Ilias E. Kanellos.

schizophrenia Candace Moore Period 1 Main idea  It tells you the main details about it  It has a lot of side effects.  Its one of the most serious.

The Role of Insulin- Like Growth Factor-1 in Schizophrenia By Karen Kiernan.

Chapter 18 Bipolar Mood Disorder. Definition 1.Bipolar I disorder # disorder in which at least one manic or mixed episode has occurred # commonly accompanied.

Bipolar Disorder. What is it? Definition: “previously known as manic depression - is a condition that affects your moods, which can swing from one extreme.

Undifferentiated Somatoform Disorder Derek S. Mongold MD.

Medication Adherence and Substance Abuse Predict 18-Month Recidivism among Mental Health Jail Diversion Program Clients Elizabeth N. Burris 1, Evan M.

Schizophrenia Derek S. Mongold MD. Citation American Psych, A. (2000). Diagnostic and statistical manual of mental disorders, dsm-iv-tr.. (4th ed. ed.).

By Danielle Chen

Bipolar II Disorder. Involves – Major Depressive Episodes and – Hypomanic Episodes Bipolar IIvsBipolar I (Hypomanic + MDD) (Manic + MDD)

Bipolar I Disorder Derek S. Mongold MD.

Faculty of Medicine, Aristotle University of Thessaloniki, Greece

Research methods- Clinical

Reduced number of peripheral natural killer cells in schizophrenia but not in bipolar disorder – a computational deconvolution study Paweł Karpiński1,

Makaric, P. 1, Bosnjak, D. 1, Kekin, I. 2, Brecic, P. 1, Jelacic, P

REPORT OF A CASE. Slim Khaldi MD, Charles Kornreich MD PHD

The role of Emotion Regulation Difficulties and Anxiety Sensitivity

Patterns of psychiatric hospital admission for schizophrenia and related psychosis in England: A retrospective cross-sectional survey Thompson A. D.¹,

Bošnjak, D. 1, Makarić P. 1, Rojnić Kuzman, M. 2

A systematic review of the relationship between substance abuse and psychotropic medication adherence: opportunities to improve outcomes for patients with.

Ferhat Yaylacı, Handan Özek Erkuran, Murat Eyüboğlu***

CAREGIVER BURDEN AMONG CAREGIVERS OF PERSONS WITH DEMENTIA AND LATE ONSET DEPRESSIVE DISORDER AND ITS ASSOCIATION WITH PERCEIVED ELDER ABUSE Presenter:

A2 unit 4 Clinical Psychology

Gottesman and Shields (1966)

The Changing Role of Medication

Presentation transcript:

SERUM LEVELS OF IGF-1 IN FIRST EPISODE PSYCHOSIS AND CHRONIC SCHIZOPHRENIA PATIENTS COMPARED TO HEALTHY CONTROLS E. Ntouros 1, E. Karanikas 1, P. Ntafoulis 1, N. Sidiropoulos 1, D. Antoniadis 2, D. Kourmpetis Military Hospital, Psychiatric Clinic, Thessaloniki, Greece 2. Aristotle University, 2nd Psychiatric Department, Thessaloniki, Greece

Introduction-Hypothesis Insulin-like growth factor 1 (IGF-1) is recently thought to play a role in the aetiopathogenesis of psychosis. Till now only 3 studies have investigated serum IGF-1 levels in psychotic patients. The aim of the study was to test the hypothesis that IGF-1 levels are altered at the onset of psychotic disorder and that they tend to deviate in a less profound extent along chronicity.

Methods We measured serum IGF-1 levels in 28 First Episode Psychosis patients (FEP), 16 patients with a diagnosis of chronic schizophrenia (CHRONIC) and 23 healthy controls (HEALTHY). FEP patients were examined at their first admission and were antipsychotic drug naive. Chronic patients were diagnosed with schizophrenia for at least 5 years and were all under antipsychotic medication. Healthy controls had no previous history of psychiatric disorders or any other known medical condition.

Results Mean IGF-1 concentration was higher in (FEP) group ( ng/ml) than in (CHRONIC) group ( ng/ml) and (HEALTHY) group (239,03 ng/ml). There is no statistically significant difference between the different groups H (3)=4.287, p=0.232 with a mean rank of for (FEP) group, for (HEALTHY) group and for (CHRONIC) group.

Conclusions/Discussion Contrary to the results of only 3 recent studies conducted on the field we found no statistical significant difference between the serum levels of IGF-1 between patients at the onset of psychosis compared to healthy controls or chronic patients. Since our groups consisted of small number of participants and the literature on the field is only minimal further studies are needed.

References: Palomino A, Gonzalez-Pinto A, Martinez M, Ruiz de Azua S, Alberich S, Mosquera F, Matute C.(2013). Relationship between negative symptoms and plasma levels of insulin- like growth factor 1 in first-episode schizophrenia and bipolar disorder patients. Prog Neuropsychopharmacol Biol Psychiatry 44: Venkatasubramanian G, Chittiprol S, Neelakantachar N, Shetty T, Gangadhar B. (2010). Effect of antipsychotic treatment on Insulin like Growth Factor -1 and cortisol in schizophrenia:a longitudinal study.Schizophr Res. 119: