Breast Cancer Surveillance Consortium (BCSC): Impact of the BCSC What is left to be done Stephen Taplin, MD, MPH, Senior Scientist NCI/DCCPS/ARP BCSC Program Director PI of BCSC site (GHC)

First Some Thanks  To the people who put this meeting together  Kathy Sedgwick  Emily Dowling  Katherine McElroy

Impressive Productivity Publications from Pooled Data Total publications 150 in in 2010 & climbing Pooled publications

In Important areas & Journals

Research Productivity as well Research A major focus of the last 5 years with major results 65 grants

And Training/mentoring Multidisciplinary exchange/discussion Junior investigators 5+ careers developed 3 career development awards 36 publications since 2005

Accomplishments  Contributions to science – a small proportion today  Methods – Performance measures Longitudinal pooled, secure data with meta-data definitions  Risk models Density and breast cancer risk  Evidence Cisnet, the USPSTF, the American College of Radiology  Variation in interpretive performance Wide variation among individuals and facilities

Accomplishments  Interventions  Measurement Automated feedback  Testing Live vs. test sets Blazing a trail for technologic advances Acrin

Impact on Clinical Care  BI-RADS  Influenced the lexicon  Interaction with ACR  MQSA  IOM report AIM  Clinicians  119 involved in testing

Beyond the science there was also productivity and a life Marriages Newborns Camaraderie Retirements

Future work  International comparisons  Test sets  Comparative effectiveness  Technology (MRI, Digital vs. Screen film)  Protocols (1 vs. 2 years)  Measurement  Performance  Feedback

Future funding  Po1-  Risk-based screening  Shared resource  Leverage the experience with sharing data  Support the teams through December

Conclusion – We are turning the page  We’ve had a productive set of chapters  Thanks to the investigators  Thanks to the many programmers, data management people, and all of the team who made the BCSC possible  Let’s go celebrate  Reception at 6 in Room Concours Terrace  Dinner at 7 – Haverford Ballroom