-19.03.9hypothetical protein LOC554226LOC554226237794_at -8.33.9neurotrophic tyrosine kinase, receptor, type 3NTRK3206462_s_at -2.73.9nuclear receptor.

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hypothetical protein LOC554226LOC _at neurotrophic tyrosine kinase, receptor, type 3NTRK _s_at nuclear receptor subfamily 6, group A, member 1NR6A _x_at C1q and tumor necrosis factor related protein 3C1QTNF _at Full length insert cDNA YN57B01no information _a_at storkhead box 2STOX _at Transcribed locus, strongly similar to NP_ G protein-coupled receptor 27;super conserved receptor expressed in brain 1 [Homo sapiens] no information227769_at zinc finger protein 403ZNF _at four and a half LIM domains 1FHL _s_at hypothetical protein FLJ23861FLJ _at interleukin 1 receptor-like 1IL1RL _at endothelin receptor type BEDNRB204271_s_at exostoses (multiple) 1EXT _at FAT tumor suppressor homolog 4 (Drosophila)FAT _at CDNA FLJ34880 fis, clone NT2NE no information _a_at sorbin and SH3 domain containing 2SORBS _at solute carrier family 2 (facilitated glucose transporter), member 3 SLC2A _s_at tissue factor pathway inhibitor 2TFPI _s_at receptor tyrosine kinase-like orphan receptor 1ROR _at forkhead box P2FOXP _at CDNA FLJ36837 fis, clone ASTRO no information227383_at adenylate cyclase activating polypeptide 1 (pituitary) receptor type I ADCYAP1R _at chemokine (C-X-C motif) receptor 4CXCR _at tissue factor pathway inhibitor 2TFPI _at WWC family member 3WWC _at GPI deacylasePGAP _at sprouty-related, EVH1 domain containing 1SPRED _at ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) ELAVL _x_at potassium inwardly-rectifying channel, subfamily J, member 2 KCNJ _at dachshund homolog 2 (Drosophila)DACH _at CFPAC-1 shPAUF Panc-1 PAUF Gene TitleGene SymbolProbe ID Supplementary Table 1. List of upregulated genes by PAUF *

activating transcription factor 6ATF _at hypothetical protein FLJ10213FLJ _at hydroxysteroid (17-beta) dehydrogenase 12HSD17B _at chloride intracellular channel 6CLIC _at no information _at hypothetical gene CG012CG _at mucolipin 3MCOLN _at hypothetical gene supported by BX647608LOC _s_at palladin, cytoskeletal associated proteinPALLD200906_s_at cyclin-dependent kinase 6CDK _at stearoyl-CoA desaturase 5SCD _at thymus high mobility group box protein TOXTOX204530_s_at RAN binding protein 17RANBP _s_at deiodinase, iodothyronine, type IIDIO _at WAS/WASL interacting protein family, member 1WIPF _s_at zinc finger, MYND domain containing 11ZMYND _at claudin domain containing 1CLDND _at exostoses (multiple) 1EXT _a_at serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 SERPINA _s_at hypothetical gene supported by BX647608LOC _at cyclin-dependent kinase 6CDK _at WWC family member 3WWC _s_at formin binding protein 1FNBP _at DDHD domain containing 1DDHD _at histone deacetylase 3HDAC _at Transcribed locusno information231513_at lymphocyte antigen 96LY _at WAS/WASL interacting protein family, member 1WIPF _at carboxypeptidase MCPM235706_at SEC24 related gene family, member D (S. cerevisiae)SEC24D215209_at phosphodiesterase 4D interacting protein (myomegalin)PDE4DIP232615_at mitogen-activated protein kinase kinase kinase 8MAP3K _at gap junction protein, alpha 10, 59kDaGJA _s_at carboxypeptidase MCPM206100_at CFPAC-1 shPAUF Panc-1 PAUF Gene TitleGene SymbolProbe ID Supplementary Table 1 - continued

kelch-like 22 (Drosophila)KLHL _at Fc receptor-like 5FCRL _at no information _at DBF4 homolog B (S. cerevisiae)DBF4B238757_at no information _at regulatory factor X, 3 (influences HLA class II expression)RFX _at sterile alpha motif domain containing 4ASAMD4A235756_at ring finger protein 34RNF _at no information _at mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) MASP _s_at suppressor of variegation 4-20 homolog 1 (Drosophila)SUV420H _at Full-length cDNA clone CL0BB018ZE07 of Neuroblastoma of Homo sapiens (human) no information41856_at no information _at oxidized low density lipoprotein (lectin-like) receptor 1OLR _at fibronectin type III domain containing 3BFNDC3B _at RNA binding motif protein 41RBM _at KIAA _at pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)PLRG _at Homo sapiens, clone IMAGE: , mRNAno information _at Transcribed locus, strongly similar to NP_ homeo box B3;homeo box 2G;homeobox protein Hox-B3 [Homo sapiens] no information237189_at zinc finger protein 545ZNF _at GRB2-related adaptor proteinGRAP235102_x_at actin related protein 2/3 complex, subunit 5, 16kDaARPC _at FGFR1 oncogene partner 2FGFR1OP _at TDP-glucose 4,6-dehydrataseTGDS237346_at epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) EGFR211551_at integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) ITGAV232797_at neuron navigator 1NAV _at paired box gene 9PAX _at acyl-CoA synthetase long-chain family member 4ACSL _a_at CFPAC-1 shPAUF Panc-1 PAUF Gene TitleGene SymbolProbe ID Supplementary Table 1 - continued

CDNA FLJ37243 fis, clone BRAMY no information228632_at PRO1496no information221155_x_at intercellular adhesion molecule 1 (CD54), human rhinovirus receptor ICAM _s_at ATP-binding cassette, sub-family G (WHITE), member 1ABCG _s_at hypothetical protein LOC338653LOC _at hypothetical protein LOC647946LOC _at CDNA clone IMAGE: no information _a_at CDNA clone IMAGE: no information230672_at pentraxin-related gene, rapidly induced by IL-1 betaPTX _at integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) ITGAV241769_at CFPAC-1 shPAUF Panc-1 PAUF Gene TitleGene SymbolProbe ID Supplementary Table 1 - continued * List of 96 genes (104 fragments) expressed at levels more than two-fold higher in Panc- 1_PAUF than in Panc-1_Mock and more than twofold lower in CFPAC-1_shPAUF than in CFPAC-1_shCtrl.