Translational Genomics Research Institute | www.tgen.org The Sarcoma Data Portal: Making High Content Sarcoma Datasets Available For All Users Jonathan.

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Translational Genomics Research Institute | The Sarcoma Data Portal: Making High Content Sarcoma Datasets Available For All Users Jonathan Keats, PhD Translation Genomics Research Institute

Translational Genomics Research Institute | Outline Some examples of other systems Outline of the initial concepts for the Sarcoma Portal

Translational Genomics Research Institute | Myeloma Cell Line Portal - Query This project includes matched CGH, exome sequencing and RNA sequencing

Translational Genomics Research Institute | Myeloma Cell Line Portal - Mutations

Translational Genomics Research Institute | Myeloma Cell Line Portal - Expression

Translational Genomics Research Institute | Multiple Myeloma Genomics Portal This supports a diverse collection of multiple datasets on multiple platforms

Translational Genomics Research Institute | Multiple Myeloma Researcher Gateway

Translational Genomics Research Institute | Sarcoma Portal Initial phase to focus on existing gene expression profiling datasets from large (>20) patient studies. – Preference for studies with overall survival or progression free survival The central design philosophy is to provide users with an easy way to interrogate datasets

Translational Genomics Research Institute | Proposed General Layout

Translational Genomics Research Institute | Kaplan-Meier Generation -Single Gene or Multiple Gene Analysis -Subset or Group Analysis -Multiple plot formats -Barplots (individual sample) -Box plots or dot plots (groups) -Histograms (dataset) -Kaplan-Meier (between groups) -Publication quality graphics -Experienced user recommendations

Translational Genomics Research Institute | Suggestions are Welcome

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