OMX PROBIOTICS

In 1908, Ellie Metchnikoff a nobel laureate working at the Pasteur Institute, discovered that ingestion of certain microorganism can displace putrefactive toxin-producing bacteria… thus preventing (and even treating) diseases, thereby prolonging life and promoting health… (this was noted among Bulgarian farmers) For the last 20 years, Dr. Iichiroh Ohhira a Japanese Microbiologist, awarded “Scientist of the Year” in 1991 after successfully encapsulating strains of good bacteria known as “ Probiotics ”.

The presence of large number of non- Super Infection Develops due to the lost of inhibitory influence of the intestinal microflora. - The Pharmacological Basis of Therapeutics - (Goodman and Gilman) Nosocomial Infection - Associated after treatment of broad spectrum antibiotics. The presence of large number of non- pathogenic bacteria provides protection to the host by suppressing the growth of potentially pathogenic bacteria. - Principles of Surgery SWARTZ 7th edition.

OMX PROBIOTICS Brand Name: OMX Origin, Founder: Ohhira, Japan Ingredients: 12 Strains of Lactobacillus and Bifidus bacteria, 18 Essential and non-essential amino acids, Vitamins B6, B12, folic acid, niacinamide, panthothenic acid, biotin, inositol, riboflavin, thiamine, Fe++, Ca, k+, phosphorus, Na+.

Most Reported Probiotics BIFIDOBACTERIA B. bifidum B. longum B. breve B. lactis Streptococcus thermophilus LACTOBACILLI L.GG L. acidophilus L.casei L.bulgaricus Saccahromyces boulardii Enterecoccus faecalis

Bacteria comprise 3.5 lbs of our TBW. 30% of fecal material consist of bacteria. Thousands of billions of bacteria resides in our system.

INTESTINAL FLORA 10^7 bacteria gram of saliva 10^4 jejunum lactobacillus-enterococcus 10^3 stomach- gastric acid 10^7 ileum mixed flora 10^12/g ileo-cecal colon bifidus bacteroids strep

MICROFLORA 85% 15% 102 strains 500 strains Good Bacteria Bad Bacteria Beneficial Friendly Symbiotic 15% 500 strains Bad Bacteria Harmful Pathogenic Opportunistic Maintain Balance Positive = Healthy Negative = Unhealthy

BENEFICIAL FUNCTIONS Prevent colonization and control the growth of pathogenic bacteria Strengthen immune system and serve as body’s first line of defense. Produce ATP and vitamins k / B-Complex and helps in the digestion of food and absorption of minerals.

BENEFICIAL FUNCTIONS Guard against CANCER. Friendly bacteria neutralize & metabolize procarcinogens & convert them back into non-carcinogenic substances. Decrease the work load of the immune system. Increase the activity of tumor killer cells and DNA repair system. “Probiotics” A Critical Review – Dr. Gerald W. Tannock 1999 “Probiotics” The Scientific Basis – Dr. Roy Fuller 1992

Choosing the Right Probiotics (free powders and capsules) The freeze drying process involves the removal of water by subjecting the bacteria to extremes of heat and cold and the application of vacuum. This drastic “ripping off” of water from a living organism disrupts its structure, function and internal environment. Addition of stabilizers and preservatives prior to freeze drying. Severe bacterial cell damage occurs if centrifugation and chemicals are used. Extensive damage to bacteria caused by freeze drying process. Powder shelf life is short. Powder absorbs water, then bacteria become activated and die away. Live bacteria in the powder have damaged walls and cannot grow properly. Transport and storage is easier, but must be refrigerated.

Choosing the Right Probiotics LIQUID PREPARATIONS (Yoghurt, etc.) Liquid preparations offer major disadvantages which relate to the instability of free organisms while in solution, harsh methods of preparation such as pasteurization, and the corrosive action of the stomach’s acid. Short shelf life (few organisms remain alive in solution after several weeks) Friendly bacteria damaged by pasteurization (exposure to high temperatures 60 to 80 deg. C) Severe bacterial cell damage occurs if centrifugation and chemicals are used. Additives and preservatives are added to stabilize the bacteria in solution. Transport and storage is difficult. Not suitable for overseas travel.

Choosing the Right Probiotics FERMENTED PASTE CONTAINING FRIENDLY BACTERIA The preparation of OMX involves the use of natural organic ingredients and a natural non-chemical fermentation process unlike any other preparation process currently used by industry. - Bacteria-functional and viable. - No damage to bacterial cell wall. - No centrifugation. - No freezing. - Storage and transport is easy. - No preservatives and additives.

Some Local Trials/Evidences on the Use of Probiotics

Acute Non-Bloody Diarrhea Community Acquired Pneumonia Allergy – Atopic Dermatitis Nosocomial Infection Dengue Hemorrhagic Fever Grade II Immune Markers for Undernourished Febrile Nuetropenia * Chronic UTI * Constipation

Summary Proven Effects in (1)diarrhea, (2)pneumonia, (3)dengue grade II, (4)nosocomial infection, (5)allergy prevention (6) Immune Markers for Undernourished at least in the local setting. Cost-effective, safe adjunct in the routine treatment of common pediatric conditions

Methods of Consumption At least room temperature Storage Early morning or Before Bedtime Ideally Empty Stomach Keep away from heat At least room temperature RuChe Philippines

FOR MORE INFORMATION GET THROUGH ME @ 0922-8007617 THANK YOU WWW.RUCHEPHILS.COM Roche P. Ruiz, MBA FOR MORE INFORMATION GET THROUGH ME @ 0922-8007617

PROBIOTICS It’s a Bacteria!!! GOOD Bacteria. “Pro-bio” (Pro-Life) A functional food medicine, which beneficially improves and restores, altered human Intestinal Microbial Balance (IMB). When taken a substantial amount offers beneficial effect on the host. - WHO

90% of ALL illnesses are associated with BAD BACTERIA ROYAL SOCIETY of MEDICINE of GREAT BRITAIN reported the 90% of ALL illnesses are caused by the Infection of the GASTRO-INTESTINAL TRACT (GIT). 90% of ALL illnesses are associated with BAD BACTERIA

OMX PROBIOTICS GENERAL KNOWLEDGE

Probiotics History meaning … “For Life" It is the opposite of antibiotics or the killing of bacteria. Dr. Hippocrates (Father of Medicine) SAID "Let your food be your medicine and your medicine your food".

Antibiotics History 1941 Antimicrobial Therapy began with the production of antibiotics called penicillin. This pharmaceutical agent become the most misuse, abuse & over use. Result of the widespread use of antimicrobial agent has been the emergence of antibiotics resistant pathogen and “superinfection” (e.g. pseudomembranous colitis – clostridium dificille) GOODMAN & GILMAN

Lactobacilli Bulgaricus: Lactose Intolerance: digestive systems lack the enzymes to break down lactose to simpler sugars. Lactobacilli Bulgaricus: It was discovered by? Dr. Stamen Grigorov (Bulgaria 1905) Lactobacilli Casei: Now !!! Called Lactobacilli Rhamnosus also called sometimes L. GG (Gorbach and Golding)

Alkaline Acidic Bacteria: Bacterium Genes (Genus) Bad Bacteria: 1. Resident 2. Transient Bacterium Genes (Genus) 1. Lactobacilli 2. Bifidobacterium 3. Streptococcus 4. Enterococcus Alkaline Bad Bacteria: Acidic Good Bacteria: means “MILK” Lacto ? Bacillus ? means “ROD-LIKE in SHAPE” Acidophilus means “ACID-LOVING”

Lactobacillus Acidophilus The large intestine houses the greatest number and the widest assortment. Lactobacillus Acidophilus is the main bacteria that resides in the Small Bowel. Lactobacillus Bulgaricus is a traveling bacteria that aids acidophilus and bifidus. Bifidus is the main bacteria that resides in the COLON?

OMX PROBIOTICS Brand Name: OMX Origin, Founder: Ohhira, Japan Ingredients: 12 Strains of Lactobacillus and Bifudus bacteria, 18 Essential and non-essential amino acids, Vitamins B6, B12, folic acid, niacinamide, panthothenic acid, biotin, inositol, riboflavin, thiamine, Fe++, Ca, k+, phosphorus, Na+.

What is Probiotics? is a LIVE microbial food medicine which beneficially improves and maintain human intestinal microbial balance. Definition by the FAO/WHO “live microorganisms which when consumed in ADEQUATE AMOUNTS, confer a health effect on the host.

Group of bacteria inhabits the intestine INTESTINAL FLORA Group of bacteria inhabits the intestine 100 trillion bacteria of 400 different strains 3.5 lbs TBW are bacteria 30% of feces are bacteria

BENEFICIAL FUNCTIONS Prevent colonization and control the growth of pathogenic bacteria Strengthen immune system and serve as body’s first line of defense. Produce ATP and vitamins k / B-Complex and helps in the digestion of food and absorption of minerals.

Choosing the Right Probiotics (free powders and capsules) The freeze drying process involves the removal of water by subjecting the bacteria to extremes of heat and cold and the application of vacuum. This drastic “ripping off” of water from a living organism disrupts its structure, function and internal environment. Addition of stabilizers and preservatives prior to freeze drying. Severe bacterial cell damage occurs if centrifugation and chemicals are used. Extensive damage to bacteria caused by freeze drying process. Powder shelf life is short. Powder absorbs water, then bacteria become activated and die away. Live bacteria in the powder have damaged walls and cannot grow properly. Transport and storage is easier, but must be refrigerated.

Choosing the Right Probiotics LIQUID PREPARATIONS (Yoghurt, etc.) Liquid preparations offer major disadvantages which relate to the instability of free organisms while in solution, harsh methods of preparation such as pasteurization, and the corrosive action of the stomach’s acid. Short shelf life (few organisms remain alive in solution after several weeks) Friendly bacteria damaged by pasteurization (exposure to high temperatures 60 to 80 deg. C) Severe bacterial cell damage occurs if centrifugation and chemicals are used. Additives and preservatives are added to stabilize the bacteria in solution. Transport and storage is difficult. Not suitable for overseas travel.

Choosing the Right Probiotics FERMENTED PASTE CONTAINING FRIENDLY BACTERIA The preparation of OMX involves the use of natural organic ingredients and a natural non-chemical fermentation process unlike any other preparation process currently used by industry. - Bacteria-functional and viable. - No damage to bacterial cell wall. - No centrifugation. - No freezing. - Storage and transport is easy. - No preservatives and additives.

FACTORS THAT ALTER THE INTESTINAL FLORA ANTIBIOTICS/CHEMOTHERAPY RADIATION THERAPY STRESSFUL LIFESTYLE FOOD – HERBICIDES, PESTICIDES, CHEMICAL, PRESEVATIVES GASTRO-INTESTINAL DISORDER

Migraine Headache / Hypertension - bad bacteria produce Tyramine. - Tyramine triggers constriction of blood vessel. Chronic Oral Ulcer - Oral microbial balance destroyed by Antibiotics / Steroids / Chlorinated water / Chemicals & Pesticides – leads to depletion of Lactobacillus Salivaricus (good bacteria) Peptic Ulcer Disease - Helicobacter Pylori – a pathogenic bacteria destroy the mucosal lining of the stomach. - acid can easily penetrate the eroded mucusa-producing ulcer Coronary Heart Disease - Studies showed that DNA protein of chlamydia pneumonia was found underneath the cholesterol plaque-atheroma of coronary artery. (British Journal of Cardiology) Gall Bladder Stone - E. Coli dis-conjugates bilirubin into insoluble bile. And theis serves as a Nidus for stone formation.

Kidney Stone - Nano bacteria Diabetes Mellitus - E. coli toxins block the receptor site, which makes the insulin inactive. Alzheimer’s Disease - E. coli bacteria forms fibers made up of amyloid, substance that makes up the plaques that accumulate in the brain. (Dr. Matthew R. Chapman – Washington University) Hypertyroidisma - Yersinia enterocolitica – a bad bacteria from intestine was found in the thyroid gland of those patients suffering from thyroid disease. Chronic U.T.I. - Depletion of Doderlie Bacillus. - Imbalance of intestinal microbial flora may also lead to chronic U.T.I. secondary to its anatomical proximity to the anus. Diarrhea - Transient pathogenic bacteria from contaminated food.

MECHANISM OF ACTIONS * Acidification of Gut Lumen * Synthesis of Antimicrobial substances * Competition for Nutrients * Competition for Receptors * Competitive Inhibition of Adhesion of Pathogen * Modification of Toxins or Toxins Receptors * Stimulation of Specific and Non-Specific Immune Response

Some Local Trials/Evidences on the Use of Probiotics

Febrile Nuetropenia Acute Non-Bloody Diarrhea Community Acquired Pneumonia Allergy – Atopic Dermatitis Nosocomial Infection Dengue Hemorrhagic Fever Grade II Immune Markers for Undernourished Febrile Nuetropenia * Constipation * CHRONIC U.T.I.

Acute Non-Bloody Diarrhea Jose Reyes Memorial Medical Center Intake of OMX Probiotics capsules (1 capsule BID for 5 days) In addition to ORS, significantly reduced the duration of Diarrhea in children compared with those who only received ORS. The mean days were shorter 3.17 days in the probiotic Group than in non-probiotic group with 5.12 days Community acquired pneumonia Jose Reyes Memorial Medical Center Intake of OMX Probiotics capsules significantly shortened the Duration of illness (cough, fever, rales, retractions, wheezing) Hospital stay and respiratory symptoms with mean of 2.4 days In the treatment group vs. 4.3 days in the control group. (1-2 capsules 2x a day)

Allergy – atopic dermatitis Jose Reyes Memorial Medical Center Intake of Probiotics resulted to a lower score on the SCORAD (SCORing Atopic Dermatitis) index, a clinical tool used to Objectively assess atopic dermatitis. 46% less incidence with Probiotics than 56% without. Nosocomial infection Philippine General Hospital Preliminary results: Intake of Probiotic capsules prevent nosocomial infection in Children with hematologic and Oncologic Diseases.

Intake of OMX Probiotics did not progress to further deterio- Dengue Hemorrhagic Fever Grade II Philippine Children Medical Center Intake of OMX Probiotics did not progress to further deterio- Ration of their condition and were able to have normalization of their Hematocrit and platelet count. HCT 3,94 (control group) and 2.16 days (experimental group) Platelet Count 5.50 (control group) & 3.33 days (experimental group) 1-2 caps/days) Immune Markers for Undernourished Philippine Children Medical Center OMX Probiotics lead to weight gain and shorter duration of infections.

Febrile Nuetropenia * Constipation * Chronic u.t.i. Cardinal Santos Medical Center * Constipation Jose Reyes Memorial Medical Center * Chronic u.t.i. Philippine Children Medical Center

Summary Proven Effects in (1)diarrhea, (2)pneumonia, (3)dengue grade II, (4)nosocomial infection, (5)allergy prevention (6)Undernourished at least in the local setting. Cost-effective, safe as adjunct in the routine treatment of common pediatric conditions

Role in Illnesses PROBIOTICS Allergy - Asthma Elevated Blood Cholesterol Helicobacter Pylori Hypertension Irritable Bowel Syndrome Inflammatory Bowel Disease

PROBIOTICS Role in Illnesses Allergy is on the rise in industrialized nations. It is estimated that the incidence of asthma in the Philippines doubled between 1980 and 2000. The hypothesis suggests that the exposure of infants to microbes before the age of six months helps the immune system mature to be more tolerant of exposure to allergens later in life. Increasing exposure to microbes must be done safely. The effects of a Lactobacillus strain on incidence of atopic eczema in 132 infants at high risk of developing eczema.

PROBIOTICS Role in Illnesses

PROBIOTICS Role in Illnesses Pregnant mothers two-to-four weeks before delivery and newborn babies through six months of age were given Lactobacillus rhamnosus GG. Infants were followed through two years of age and incidence of recurring atopic eczema was recorded. The study reported a 50% drop in incidence of recurring atopic eczema in the group receiving the probiotic supplement.

PROBIOTICS Role in Illnesses A follow up study of these same children indicated that these same trends were still present at 4 years of age. These results suggest that exposure to the right types of microbes early in life may decrease the risk of allergy.

PROBIOTICS Role in Illnesses Elevated Blood Cholesterol. Cholesterol is essential for many functions in the human body. It acts as a precursor to certain hormones and vitamins and it is a component of cell membranes and nerve cells. But, elevated levels of total blood cholesterol or other blood lipids are considered risk factors for developing coronary heart disease.

PROBIOTICS Role in Illnesses Researchers found that the bacteria actually can help control serum cholesterol in two ways. First, as the bacteria grow in the intestinal tract, they take up some of the cholesterol that is present, and it becomes associated with the cells as the bacteria grow. Second, at least part of the cholesterol actually becomes incorporated into the bacterial cells. Either way, the cholesterol becomes unavailable for absorption from the intestine into the blood.

PROBIOTICS Role in Illnesses Probiotic cultures have been evaluated for their effect on serum cholesterol levels. Clinical studies on the effect of lowering cholesterol or (LDL) low-density lipid levels in humans. There have been human studies that suggest that blood cholesterol levels can be reduced by consumption of probiotic-containing dairy foods by people with elevated blood cholesterol.

PROBIOTICS Role in Illnesses Helicobacter pylori is a bacterium which colonizes the stomach and can cause gastric ulcers and gastric cancer. The effect of probiotics on H. pylori has been studied. Mechanistic studies in laboratory assays or in animal models have shown that antibacterial substances including (but not limited to) organic acids produced by some lactobacilli inhibit the growth and survival of this pathogen. Results in humans suggest that some probiotic strains or milk fermented with a probiotic strain can reduce metabolic activity or colonization by H. pylori.

PROBIOTICS Role in Illnesses Probiotics have also been used to manage side effects of triple antibiotic therapy used to treat Helicobacter pylori infections. In these studies, the use of probiotics decreases the side effects of antibiotics, improves patient compliance with taking the prescribed therapy, and increases the rate at which Helicobacter pylori is eradicated (Lionetti et al. 2006; Myllyluoma et al. 2005; Sheu et al. 2006; Sykora et al. 2005).

PROBIOTICS Role in Illnesses Irritable bowel syndrome (IBS) is a functional bowel disorder that can be characterized by symptoms of abdominal pain, cramps, gas, bloating, diarrhea and constipation. Surveys estimate the prevalence rate ranging from 10-20% of the adult population and the condition is diagnosed 3 times more often in women than men (FDA Consumer Magazine, July-Aug, 2001).

PROBIOTICS Role in Illnesses It shows controlled studies that have been conducted evaluating probiotics and IBS (Ringel-Kulka T, Ringel Y. Probiotics in irritable bowel syndrome: has the time arrived? Gastroenterology. 2007 Feb;132(2):813-6). Some symptom relief (primarily from diarrhea or abdominal pain or bloating) has been reported in studies published to date (Whorwell PJ, Altringer L, Morel J, Bond Y, Charbonneau D, O'Mahony L, Kiely B, Shanahan F, Quigley EM. Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome. Am J Gastroenterol. 2006 Jul;101(7):1581-90.).

PROBIOTICS Role in Illnesses Inflammatory bowel diseases such as “Ulcerative Colitis” and “Crohn’s disease”, are serious intestinal diseases that can lead to the surgical removal of the colon. The cause of these diseases is not known but it has been hypothesized that an intolerance to the normal microbiota in the gut leads to inflammation and resulting pathology. The role of gut flora in the progression of these diseases has led some researchers to study the impact certain probiotic bacteria might have on maintaining the state of reduced inflammation that occurs during remission stages of the diseases.

O M X PRODUCT PRESENTATION

Lactobacillus Acidophilus

Lactobacillus Acidophilus This bacterium thrives in more acidic environments than most related microorganisms (pH 4-5 or lower) and grows best at 45 degrees Celsius. Lactobacillus acidophilus occurs naturally in the human intestine, mouth, and vagina. Lactobacillus acidophilus ferments lactose into lactic acid. Lactobacillus acidophilus itself (a homofermentative microorganism) produces only lactic acid. Like many bacteria, Lactobacillus acidophilus can be killed by excess heat, moisture, or direct sunlight.

Lactobacillus Bulgaricus

Lactobacillus Bulgaricus Lactobacillus bulgaricus is one of several bacteria used for the production of yogurt. First identified in 1905 by the Bulgarian Dr. Stamen Grigorov, it is named after Bulgaria. The bacterium feeds on milk and produces lactic acid which also helps to preserve the milk. It breaks down lactose and is often helpful to sufferers of lactose. While fermenting milk, Lactobacillus bulgaricus produces acetaldehyde, which perfumes yogurt. Some of the biggest importers of the bacterium are Japan, USA and the EU.

Lactobacillus Rhamnosus

Lactobacillus Rhamnosus Lactobacillus casei is a transient, anaerobic microorganism of genus Lactobacillus found in the human intestine and mouth. As a lactic acid producer, it has been found to assist in the propagation of desirable bacteria. This particular species of lactobacillus is documented to have a wide pH and temperature range, and complements the growth of Lactobacillus acidophilus, a producer of the enzyme amylase (a carbohydrate-digesting enzyme). It is known to improve digestion and reduce milk intolerance and constipation.

Lactobacillus Helveticus

Lactobacillus Helveticus Lactobacillus helveticus is a homofermentative thermophilic lactic acid bacterium. Our data contribute to the description of microbial heterogeneity in Lactobacillus helveticus and provide a more solid basis for understanding the functional and ecological significance of the presence of different Lactobacillus helveticus biotypes in natural dairy starter cultures. This bacterium works as a support in all the group and it has significantly powerful in terms of assistance.

Lactobacillus Fermentum

Bifidobacterium Longum

Lactobacillus Fermentum Lactobacillus fermentum was selected for further study, since, in addition to its intrinsically high adhesion rate, this organism was found to exhibit a “preferential binding” to the follicle-associated epithelium of the Peyer's patches compared with its level of binding to the mucus-secreting regions of the small intestine. Kulani

Lactobacillus Plantarum

Lactobacillus Plantarum Lactobacillus plantarum is a widespread member of the genus Lactobacillus. It is in saliva (from which it was first isolated). It has the ability to liquefy gelatin. Lactobacillus plantarum has one of the largest genomes known among the lactic acid bacteria and is a very flexible and versatile species.

Bifidobacterium Bifidus

Bifidobacterium Bifidus Bifidus (Bifodobacterium bifidum) lowers the pH of the intestine, manufactures specific B vitamins, promotes immune function, and supports the health of the large intestine (colon). Bifidus is a natural inhabitant of the large intestine that helps with the absorption of water from food and the processing of remaining waste. Good intestinal flora in the large intestine can help inhibit gas and bloating.

Bifidobacterium Infantis

Bifidobacterium Longum Scientists have sequenced the genome of one of the most important residents in the human gastrointestinal tract, a bacterium that keeps the digestive system running smoothly, blocks the growth of harmful bacteria, and boosts the immune system. The microbe, called Bifidobacterium longum, is often the dominant bacterium found in humans.

Bifidobacterium Breve

Bifidobacterium Breve Bifidobacteria are natural inhabitants of the human gut microbiota, representing up to 91% of the total gut population in breast-fed babies. Some strains of the genus Bifidobacterium are considered probiotics and can exert several health-promoting effects. Bifidobacterium breve is one of the species more often found in infants. The intestinal microbiota is continuously exposed to cytotoxic agents, including antibiotics. Recent evidence indicates that Bifidobacterium breve is generally more resistant to antibiotics than other Bifidobacterium species

Bifidobacterium Lactis

Bifidobacterium Lactis Effects of Bifidobacterium lactis Bb12 Supplementation on Intestinal Microbiota of Preterm Infants: a Double-Blind, Placebo-Controlled, Randomized Study. J Clin Microbiol. 2006 November; 44(11): 4025–4031.

Streptococcus Thermophilus

Streptococcus Thermophilus Streptococcus thermophilus (official name Streptococcus salivarius subsp. thermophilus). It is also classified as a lactic acid bacterium (LAB). Streptococcus thermophilus is found in milk and milk products. (it does not survive the stomach) and generally used in the production of yogurt.

Antibiotics you need more Probiotics. THERAPEUTIC USES Restore improves and maintain the intestinal microbial balance , after antibiotics, chemotherapy, radiotherapy and other factors that alter the Intestinal flora. “One (1) to three (3) capsule per day” Antibiotics you need more Probiotics. Why? Along with killing the pathogenic bacteria, antibiotic destroy The balance by destroying good bacteria in your digestive system. “Ideally, you should start repopulating your digestive system with good bacteria-probiotics when you begin your course of antibiotics.”

ANTIBIOTIC(S) PRODUCED ANTIBIOTICS PRODUCES BY BENEFICIAL BACTERIA BACTERIA TYPE SOURCE ANTIBIOTIC(S) PRODUCED BIFIDOBACTERIUM BIFIDUM RESIDENT BIFIDO-ENRICHED MILK SUPPLEMENTS BIFIDIN LACTOBACILLUS ACIDOPHILUS ADIDOPHILLUS ENRICHED MILK SUPPLEMENTS ACIDOLIN, ACIDOPHILIN, LACTOBACILLIN, LACTOCIDIN LACTOBACILLUS BREVIS TRANSIENT MILK, KEFIR, CHEESE, SAUERKRAUT LACTOBREVIN LACTOBACILLUS BULGARICUS YOGURT, CHEESE SUPPLEMENTS BULGARICAN STRETOCOCCUS LACTIS RAW MILK RAW MILK PRODUCTS, CHEESE, COTTAGE CHEESE, BUTTERMILK NISIN