1 Protein Crystallography. 2 Ban, N., Nissen, P., Hansen, J., Moore, P. B., Steitz, T. A. Science 289 pp. 905 (2000)

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Presentation transcript:

1 Protein Crystallography

2 Ban, N., Nissen, P., Hansen, J., Moore, P. B., Steitz, T. A. Science 289 pp. 905 (2000)

3 Protein Crystallography Aspecific acid phosphatase from E. coli

4 DNA Polymerase

5 ATP synthesis Cell (plant) Cell (plant) mitochondria

6 ATP synthesis Cell Inner mitochondrial membrane Inner mitochondrial membrane

7 ATP synthesis Surface of the inner mitochondrial membrane Surface of the inner mitochondrial membrane

8 ATP synthesis Section of the inner mitochondrial membrane Section of the inner mitochondrial membrane NADH oxidase Cytochrome Citochrome C oxidase ATP synthase

9 fragment F1 Abrahams, J. P., Leslie, A. G., Lutter, R., Walker, J. E. Nature 370 pp. 621 (1994)

10 ATP synthase The ADP binding site in ATP synthase

11 ATP synthase ATP synthase mechanism