DEANNA DAILEY DR. CHAN’S HUMAN PHYS G BLOCK Why do some allergens effect different people in different ways?

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Presentation transcript:

DEANNA DAILEY DR. CHAN’S HUMAN PHYS G BLOCK Why do some allergens effect different people in different ways?

What is an allergic reaction? An allergic response is when an antibody binds to and antigen and irritation occurs. Types of reactions:  Rash or hives  Swelling: epically of the lips, tongue, throat, face  Dizziness  Nausea/ diarrhea  Anaphylaxis ctype=2&docid=8700

Steps to an allergic reaction 1. The antigen enters the body 2. Triggered B-cells to produce IgE antibodies 3. These antibodies target the specific allergen 4. This releases histamine to battle the allergen causing a reaction. Depending on how sensitized, the genes of the person, or how much histamine is released, the person can have a mild or major reaction. obili/biocourse/allergies.ht ml

Why are there different effects? Genes  MHC  Controlled by different genes and they have many different variations.  Just because you are disposed to it, does not mean that you will have the allergy. Socioeconomic background  Immunity towards allergens was a defense mechanism  Variation in total and specific IgE: effects of ethnicity and socioeconomic status Exposure  The more you are exposed, the worse the symptoms can be.

Works Cited Celedon, J. C. "Variation in Total and Specific IgE: Effects of Ethnicity and Socioeconomic Status." PubMed.gov (2005): n. pag. Web. 15 Jan "Allergic Reactions: MedlinePlus Medical Encyclopedia." U.S National Library of Medicine. Ed. Stuart I. Henochowicz, David Zieve, and Isla Ogilvie. U.S. National Library of Medicine, 10 May Web. 23 Jan Asthma and Allergy Foundation of America. "IGE'S ROLE IN ALLERGIC ASTHMA." Asthma and Allergy Foundation of America. Asthma and Allergy Foundation of America, Web. 25 Jan Asthma and Allergy Foundation of America. "Asthma and Allergy Foundation of America - Information About Asthma, Allergies, Food Allergies and More!" WHAT CAUSES ALLERGIES. Asthma and Allergy Foundation of America, Web. 25 Jan