12/2013 The Present Evolution of Liver Transplantation in Europe EUROPEAN LIVER TRANSPLANT REGISTRY 28 countries - 155 institutions 118,441 transplantations.

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Presentation transcript:

12/2013 The Present Evolution of Liver Transplantation in Europe EUROPEAN LIVER TRANSPLANT REGISTRY 28 countries institutions 118,441 transplantations - 106,849 patients From May 1968 to December

12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

12/2013 EUROPEAN LIVER TRANSPLANT REGISTRY 28 countries institutions 118,441 transplantations - 106,849 patients From May 1968 to December

12/2013 Evolution of 118,364 Liver Transplantations in Europe * The decrease is owed to the fact that some centers had a delay in the updating of their data to the current development of a new data reporting system, *

12/2013 Evolution of the number of Liver Transplantations reported to the ELTR

12/2013 Evolution of the number of Liver Transplantations by Center

12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

12/2013 Evolution of Donor Age 05/1968 – 12/2013

12/2013 Gender and Age distribution of Liver Donors 01/ /2013

12/2013 Graft Survival according to Donor Age in Europe 01/ /2013

12/2013 Graft Survival according to Donor Age in Elective Liver Transplantation 01/1988 – 12/2013

12/2013 Graft Survival according to Donor Age in Urgent Liver Transplantation 01/ /2013

12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

12/2013 Age and Sex of Recipients 05/1968 – 12/2013

12/2013 Evolution of Recipient Age 05/1968 – 12/2013

12/2013 Patient Survival according to Recipient Age 01/ /2013 p Log Rank =

12/2013 Patient Survival according to Adult Recipient Age 01/ /2013

12/2013 Proportion of Pediatric Transplantation by Country 01/ /2013

12/2013 Primary Indication of Liver Transplantation in Pediatric Patients 05/ /2013

12/2013 Survival according to Children Recipient Age 01/ /2013 PatientGraft

12/2013 Survival of Children < 2 yrs according to the Main Indication in Europe 01/ /2013

12/2013 Survival of Children >= 2 yrs according to the Main Indication in Europe 01/ /2013

12/2013 Graft Survival according to Adult Recipient Age 01/ /2013

12/2013 Primary Indications of Liver Transplantion in Elderly Patients (>= 60 Years) 01/ /2013

12/2013 Survival of Elderly Recipients (>= 60 Years) according to the Main Indication in Europe 01/ /2013

12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

12/2013 * Others :Budd Chiari : 869 Benign liver tumors or Polycystic diseases : 1334 Parasitic diseases : 84 Other liver diseases : 2047 Primary Diseases leading to Liver Transplantion in Europe 01/ /2013

12/2013 Primary Indications of Liver Transplantion in Europe 01/ /2013

12/2013 Evolution of Primary Diseases leading to Liver Transplantation in Europe 05/ /2013

12/2013 Primary Diseases leading to Liver Transplantion by Country 01/ /2013

12/2013 Primary Diseases leading to Liver Transplantation in Adult Recipients 01/ /2013

12/2013 Patient and Graft Survival following Liver Transplantation 05/1968 – 12/2013

12/2013 Patient Survival according to the Year of Liver Transplantation 05/1968 – 12/2013

12/2013 Patient Survival according to the Indication 01/ /2013

12/2013 Patient Survival according to the 1st Indication 01/1988 – 12/2013

12/2013 Graft Survival according to the Urgency of Liver Transplantation in Europe 01/ /2013

12/2013 Graft Survival according to ABO Compatibility in Elective Liver Transplantation 01/ /2013

12/2013 Graft Survival according to ABO Compatibility in Urgent LT 01/ /2013

12/2013 Liver Transplantation in Europe Indications of Cirrhosis 01/ /2013

12/2013 Evolution of Indications for Cirrhosis in Europe

12/2013 Survival of Patients with Cirrhosis as the First Indication (1) 01/ /2013

12/2013 Survival of Patients with Cirrhosis as the First Indication (2) 01/ /2013

12/2013 Primary Indications of Liver Transplantation For Virus related Cirrhosis in Europe 01/ /2013

12/2013 Survival of Patients with Virus related Cirrhosis as the First Indication 01/ /2013

12/2013 Survival of Patients with Virus related Cirrhosis as the First Indication 01/ /2013

12/2013 Survival of Patients with Virus related Cirrhosis as the First Indication 01/ /2013

12/2013 Liver Transplantation in Europe Indications in Hepato-Biliary Cancers 01/ /2013 Others:Hepatoblastoma: 261 Epithelioid hemangioendothelioma: 186 Angiosarcoma: 20

12/2013 Evolution of Indications for Hepato-Biliary Cancers in Europe 05/ /2013

12/2013 Survival of Patients with Liver Cancer as the First Indication 01/ /2013

12/2013 Survival of Patients with HCC with and without underlying Cirrhosis 01/ /2013

12/2013 Primary Indications of Liver Transplantation In Patients with Acute Hepatic Failure 01/ /2013

12/2013 Survival of Patients with Acute Hepatic Failure as the First Indication 01/ /2013

12/2013 Primary Indications of Liver Transplantation in Patients with Cholestatic Diseases 01/ /2013

12/2013 Survival of Patients with Cholestatic Diseases as the First Indication 01/ /2013

12/2013 Primary Indications of Liver Transplantation in Patients with Metabolic Diseases 01/ /2013

12/2013 Survival of Patients with Metabolic Diseases as the First Indication 01/ /2013

12/2013 Indications of Liver Transplantation for Other liver diseases in Europe 05/ /2013

12/2013 Survival of Patients with Other Liver Diseases as the First Indication 01/ /2013

12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

12/2013

Graft Survival in Liver Transplantation only vs Liver Combined to other Organ Transplantation 01/ /2013

12/2013 Graft Survival according to the Site of Transplantation in Elective LT 01/ /2013

12/2013 Type of Liver Graft in Europe according to the Date of Transplantation

12/2013 Graft Survival according to the Type of Graft 01/ /2013

12/2013 Alternatives to the Use of the Full Size Cadaveric Liver Grafts in Europe

12/2013 Graft Survival according to the Type of Graft 01/ /2013

12/2013 Graft Survival according to the Type of Graft in Elective LT 01/ /2013

12/2013 Graft Survival according to the Type of Graft in Urgent LT 01/ /2013

12/2013 Graft Survival according to the Cold Ischemic Time in UW Elective LT 01/ /2013

12/2013 Graft Survival according to the Cold Ischemic Time in UW Urgent LT 01/ /2013

12/2013 Auxiliary vs Non Auxiliary Graft Survival in Elective Liver Transplantation 01/ /2013

12/2013 Auxiliary vs Non Auxiliary Graft Survival in Urgent Liver Transplantation 01/ /2013

12/2013 The Present Evolution of Liver Transplantation 1. General evolution of LT in Europe 2. Donor data 3. Recipient data 4. Indications and results 5. Evolution of techniques 6. Mortality and retransplantation

12/2013 Liver Transplantation in Europe Mortality and Retransplantation 01/ /2013

12/2013 Mortality and Retransplantation According to Recipient Age 01/ /2013

12/2013 Mortality and Retransplantation According to the 1st Indication 01/ /2013

12/2013 Graft Survival according to the Number of Liver Transplantations in Europe 01/ /2013

12/2013 Graft Survival according to the number of the LT in Elective Cases 01/ /2013

12/2013 Graft Survival according to the number of the LT in Urgent Cases 01/ /2013

12/2013 Patient Survival according to the number of Liver Transplantations 01/ /2013

12/2013 Patient Survival according to the number of LTs in Elective cases for the 1st LT 01/ /2013

12/2013 Patient Survival according to the number of LTs in Urgent cases for the 1st LT 01/1988 – 12/2013

12/2013 Mortality following the 1st LT 01/ /2013

12/2013 Causes of Retransplant following the 1st LT 01/ /2013

12/2013 ELTR Coordination Committee René Adam, MD, PhD. Custodian Vincent Karam, PhD. Data Manager Valérie Delvart, MA. Biostatistician Anne-Marie Lammerant Secretary European Liver Transplant Registry Hôpital Paul Brousse Centre Hépatobiliaire 12 Avenue Paul Vaillant Couturier Villejuif, France Tel www,eltr.org

12/2013 the support of: The ELTR continue to evolve thanks to the participation of the 153 centers and to: the colaboration with: