I2b2 CICTR Phase 3: Able to query multi-institutional anonymized PHI data 5+ million anonymized patient records across UW, UCSF and UCD. up to 5 year retrospective.

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Presentation transcript:

i2b2 CICTR Phase 3: Able to query multi-institutional anonymized PHI data 5+ million anonymized patient records across UW, UCSF and UCD. up to 5 year retrospective at UCSF, UCD, 3 years at UW Domain Diabetes Cardiovascular disease Driving use cases power calculations for cohort recruiting Prep to research aggregate data studies Intended users: Clinical/translational PI’s Study recruiters Public Health researchers

Four parallel processes Technical - IT/development/implementation/testing Governance - Data Use Agreements/IRB institutional alignment Ontology - Terminologies/semantic alignment Evaluation - Process, outcomes and usability evaluation

Site ecosystems Compatible server architectures/different DB environments architecture environments “Identical” I2b2 environments Common ETL and anonymization processes Common development environments Common knowledge environment Broadly similar governance process

Human resources needed Formal (e.g. – paid) – Informaticians – ETL analysts – Terminologists – Software architects/Developers – Usability/Evaluation researchers – Informatics/Information science students – IT staff Informal (e.g. – priceless) – Support of project at highest institutional and regulatory levels - CIO/CTO – (new!) clinicians/clinical researchers

I2b2 CICTR Available and anticipated data elements DemographicsDiagnosesMedicationsLaboratory AgeDate of diagnosesDate of encounterDate of lab GenderICD-9 numeric codesMedication name (generic/brand) Lab values Race/EthnicityiCD-9 supplemental classifications influencing health status Dose form Geocode (3 digit zip prefix) ICD-9 supplemental classification of external causes of injury and poisoning Vital status Marital status Language (tbd) Religion (tbd)