Media Briefing Saturday, April 16th 10:00 am – Media briefing begins Announcement of poster winners and a short presentation from some of the winning authors Introduction of Yehuda Handelsman, MD, FACP, FACE, FNLA as the new President of AACE 10:25 am – Floor opens to questions from the media 10:30 am – Media Briefing adjourns

OMENTECTOMY ADDED TO ROUX-EN-Y GASTRIC BYPASS IMPROVES GLUCOSE AND ADIPOKINES AT 90 DAYS: A RANDOMIZED, CONTROLLED TRIAL TH Dillard 1, JQ Purnell 1, MD Smith 2, J Laut 2, W Raum 2, D Hong 3, E Patterson 2 1.Department of Medicine, Division of Endocrinology, Diabetes, and Clinical Nutrition. Oregon Health & Science University, Portland, OR 2.Department of Surgery, Legacy Good Samaritan Hospital, Portland, OR; 3.Department of Surgery, St. Joseph's Hospital, McMaster University, Hamilton, Ontario, Canada AACE 2011

 Coagulation abnormalities in Diabetes Mellitus type 2 and microvascular complications Ritu Madan MD

Study design  Single center case control study between  60 patients with diabetes, 20 with and 40 without complications (nephropathy, retinopathy, neuropathy)  Equal number of males and females  Evaluation of major coagulation parameters

RESULTS

Results (contd.) DMDM WITH COMPLICATIONS P-valueSignificance Platelet Count1.93± ± NS PT14.1± ± NS PTT34.5± ± NS Fibrinogen239.5± ± NS AT III95.8± ± NS Protein C101.85± ± NS Protein S63.05± ± S PAI ± ± S vWF123.19± ± S Factor V98.65± ± NS Factor VIII97.37± ±3.90.6NS Factor IX98.9± ± NS

Conclusions  Microvascular complications of Type-2 Diabetes are associated with changes in coagulation parameters.  Differences in coagulation parameters were seen in diabetics with complications of nephropathy and retinopathy compared to diabetics without these complications.  The magnitude of the coagulation abnormalities is unlikely to cause symptomatic thrombotic events and hence may be clinically silent.