Amino Acids. Properties of Amino Acids Ques. 4: Use the above structures to answer the questions below: a. Which amino acid is most polar? b. Which.

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Presentation transcript:

Amino Acids

Properties of Amino Acids Ques. 4: Use the above structures to answer the questions below: a. Which amino acid is most polar? b. Which amino acid is least polar? c. Which amino acid has an acidic side chain? d. Which amino acid has a basic side chain?

Properties of Amino Acids Ques. 5: Use the below structures to answer the questions: a. Which amino acid is most polar? b. Which amino acid is least polar? c. Which amino acid is the most polar looking at thr and ser? d. Which amino acid is the least polar looking at asp and glu?

Amino Acids Zwitterion - acid and amine react with each other internally.

Amino Acids -> -> Increasing pH -> -> pH << pK << pH Acids: HA molecular A - ionic Bases: BH + ionic B molecular

Amino Acids -> -> Increasing pH -> -> pH << pK << pH Acids: HA molecular A - ionic Bases: BH + ionic B molecular

Amino Acids -> -> Increasing pH -> -> pH << pK << pH Acids: HA molecular A - ionic Bases: BH + ionic B molecular

Amino Acids

Separations of Amino Acids

Amino Acids -> -> Increasing pH -> -> pH << pK << pH Acids: HA molecular A - ionic Bases: BH + ionic B molecular Mixture of val pI = 6; asp pI = 2.8, lys pI = 9.7 in a buffer at pH = 6. What is the form of each?

Reactions Amino Acids - Salt Formation Acid + amine --> salt (acid donates H+ to amine)

Reactions Amino Acids - Disulfide 2 thiols + (O) --> disulfide + HOH

Synthesis of a peptide Amine + acid --> amide + HOH

Synthesis of a peptide Amine + acid --> amide + HOH

Synthesis of a peptide Write repeating units of backbone and add side chains