Proteins are made of amino acids. A protein is a chain of amino acids That fold into a particular shape.

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Presentation transcript:

Proteins are made of amino acids

A protein is a chain of amino acids That fold into a particular shape

Primary Structure: Elastin

Secondary Structure:  Helix

Secondary Structure:  Sheet

Tertiary Structure

Carboxyl Group Amino Group Peptide Bond Formation

Figure 3-4. Steric limitations on the bond angles in a polypeptide chain (A) Each amino acid contributes three bonds (red) to the backbone of the chain. The peptide bond is planar (gray shading) and does not permit rotation. By contrast, rotation can occur about the C α –C bond, whose angle of rotation is called psi (ψ), and about the N–C α bond, whose angle of rotation is called phi ( ϕ ). By convention, an R group is often used to denote an amino acid side chain (green circles). (B) The conformation of the main-chain atoms in a protein is determined by one pair of ϕ and ψ angles for each amino acid; because of steric collisions between atoms within each amino acid, most pairs of ϕ and ψ angles do not occur. In this so-called Ramachandran plot, each dot represents an observed pair of angles in a protein. (B, from J. Richardson, Adv. Prot. Chem. 34:174–175, © Academic Press.) Steric Limitations to Bond Angles

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TEAM 1 AhmetSerine & Proline JessyMethionine & Glycine SamGlutamic Acid & Alanine CharlieValine & Glutamic Acid TEAM 2 AshleyCystein &Tryptophan CoreyThreonine&Aspartic Acid MaxHistidine & Proline JohnIsoleucine & Threonine TEAM 3 JeremyGlycine & Proline Zack J.Lysine & Valine CarsonAsparagine & Glutamine SarahProline & Phenylalanine TEAM 4 SarahProline & Histidine CarlyPhenylalanine & Glycine DominiqueLysine & Serine TrevorAspartic Acid & Valine TEAM 5 AakashLeucine & Tyrosine Zack P.Glutamine&Methionine ShaneAlanine & Cystein KarstenArginine & Isoleucine Team 6 NickPhenylalanine & Glycine ChristianTyrosine & Proline HunterTryptophan & Glycine

Each of you will build your amino acid. Then within your group you will form peptide bonds between your amino acids to create a small “protein” or poly-peptide.