1 Confidential, for internal planning purposes only. Not to be shared or distributed outside of the BMS/AZ saxagliptin/dapagliflozin collaborative teams. Performance Report Executive Summary Timeframe: 4/1/10 – 4/30/10 Presented May 19, 2010

2 Executive Summary March'10  April Visit Volume Improved Both visit volume and daily average visits improved over March (Slide #3)  Optimized Search Spend Ups Branding Increased spend and flat CTR brought more clicks; fewer bounces upped engagement (Slide #7)  Directs Dominate Registration Sources Registration rate doubled, volume also up; almost all traffic sources had more regs (Slide #8)  Most Web Activators Are Current Onglyza Users  Redemptions Per Redeemer Reaches Two  Half The Redemptions Occur Within Two Weeks  Recommendations (Slide #22)

April Visit Volume Improved  Visits Volume improved in April by +9% – Avg. Daily Visits were up by +5% over March – Paid Search at 82% Share +11% in April – Display at 2% was up by +303%; Referreds at 1% down -40% (due to HCP ad tracking) Traffic>>Source by Month Source: Google Analytics, NetInsight. 3 HCP Banners

Directs Dominate Registrations  92% from Unpaid Sources – 70% Direct Brand Access – 16% Organic Search but branded – 6% Referral of which 3% from InternetDrugCoupons.com  8% from Paid Search DTC CRM>>Value Card Registration Rate & Sources Trend Source: Google Analytics, NetInsight. 4

IDC Is A Growing Reg Source  An +80% Increase in Visitors from InternetDrugCoupons.com since January – +100% Increase in Registrants  Amazing 22% Registration Rate from Engaged Users (2.7 PVs/Visit) – 59 Registrations YTD: Cost = $0 – Using Paid Search converters as a baseline, over $50,000 in CPA value (YTD) – Implications for Free Trial Program strategy DTC CRM>>Value Card Registration Sources Source: NetInsight. 5 Direct Growth!

6 7,500 Redeemed-To-Date  55% of activated cards have been redeemed, compared to 53% last month.  Same day redemptions increased very slightly (36% to 37%).  After 4 th Week 1 st redemptions increased from 3% to 4%. Total Cards Activated = 13,480 Total Cards Redeemed = 7,359 Key: Time to first redemption card count card count % DTC CRM >>Overall first redemptions by time interval

7 Time To Redemption Percentages Steady Percentage of cards making first redemption on the same day and within one week of activation  Apart from Jan and Apr, redemption proportions have held steady: Same day 35-40% Through 1st Week44-49%  The dip in Apr is likely to be at least partially due to redemption data which has not yet been received.

8 Steady Growth Across All Value Card Metrics Cumulative Activity by Month  Redemptions per redeemer greater than 2.  Redemptions per activation greater than 1.  Redeemer rate holding steady at just above 50%

9 Reminder Program Notes And Assumptions  Through Apr-10, the time from mailing to first redemption ranges from 1 to 71 days.  Just over 50% of these first redemptions occur within 14 days of the mailing.  For the purposes of this analysis, any first redemptions that occur after a reminder mailing was sent are being counted as influenced by the mailing.  Is there a desire to exclude from the reminder program count first redemptions which occur more than a specified number of days from mailing?

10 First Redemptions From Reminders Steady First Redemptions by Reminder Mail Type by Week  5% of those who received a timely reminder have made their first redemption.  Apart from the jump in early to mid-April, total weekly redemptions have been relatively steady, ranging from 24 to 37.  Jump in redeemers on 10-Apr and 17-Apr primarily due to high numbers of reminders sent on 3-Apr and 10-Apr (2 nd catch up). Total Redeemers Direct Mail:

DTC Recommendations Confidential, for internal planning purposes only. Not to be shared or distributed outside of the BMS/AZ saxagliptin/dapagliflozin collaborative teams. March'10 1.Web Site a)Integrate AZ OnglyzaCampaign data into site tracking [DMS] b)Implement tracking across DTC/HCP/Nutrition Tracker/Ad Server Tags [DMS] 2.DTC Advertising/Media a)Paid Search [MV] i.Optimization or bidding changes that led to higher bounce rate ii.Ascertain Branded vs. Unbranded ad copy test viability iii.Define automated reporting also for Organic Search [Rosetta, DMS, MV] 3.CRM Control Group a)A small percentage of potential recipients in each mailing should be held aside as a control group; this will allow us to directly and statistically calculate lift in time to first redemption, redemption percentage, and redemption frequency. [DMS] 4.Research a)Track Januvia activity via Compete data [DMS] b)Monitor Demographic/lookalike behavior (Quantcast) [DMS] 11

12 Proportions of WEB* activated by card type Most WEB Activated Are Current Onglyza Users  Over 60% of both Physician and Web card activators indicated that they are current Onglyza users.  Proportions are nearly the same for both card types. Current Onglyza User * No question about current Onglyza use appears in the TM scripts and no “Yes” responses to such a question appear in the database for the TM activation channel.