Amides

O R-C NH 2 Alkanoamide

Common Amides

Formamide O H-C NH 2 Methanoamide

Acetamide O CH 3 -C NH 2 Ethanoamide

Amides O CH 3 -CH 2 -C NH 2 Propanoamide

Amides O -C NH 2 Benzoamide

N-methylbenzoamide O -C NH CH 3

Making Amides

Add Acids & Amines O R-C-OH + :NH 3 O R-C-O - + NH 4 +

Dehydration Syn O R-C-O - + NH 4 + O R-C-NH 2 + H 2 O Heat

Add Acids & Amines O R-C-OH + :NH 3 O R-C-NH 2 + H 2 O

Dehydrating Agents H 2 SO 4 P 2 O 5

Acetic acid + Met amine O H 3 C-C-OH + CH 3 NH 2

N-methylacetamide O CH 3 H 3 C-C-NH + H 2 O

Predict Products Dehydration synthesis of benzoic acid + cyclopropylamine

Drill: Draw the organic reactant; then, draw & name the organic product of the dehydration synthesis of propanoic acid + ammonia.

Esters + Amines O R 1 -C-O-R 2 + :NH 3

Amides + Alcohols O R 1 -C-NH 2 + R 2 -OH

Methyl benzoate + A O -C-O-CH 3 + :NH 3

Benzoamide & MeOH O -C-NH 2 + HO-CH 3

Anhydrides + Amines O O R 1 -C-O-C-R 2 + :NH 3

Amides + Acids O R 1 -C-NH 2 O + R 2 -C-OH

Polyamides

AA + HDA O O n HO-C-(CH 2 ) 4 -C-OH + n H 2 N-(CH 2 ) 6 -NH 2 -water

Nylon 66 O O -(-C-(CH 2 ) 4 -C NH -(HN-(CH 2 ) 6 n

6-aminohexanoic acid O x HO-C-(CH 2 ) 5 -NH 2 -water

Nylon 6 O x -(-(CH 2 ) 5 -C-NH-)-

COOH + COOH H2NH2NH2NH2N

C=O + H 2 O C O HN

Nitriles

Making Nitriles O R-C-NH 2 Heat Dehydration Dehydrate amides

Nitrile + Water R-C-N: + H 2 O

Common Nitriles R-C=N

Acetonitrile CH 3 -C=N

Hydrogen Cyanide H-C=N

Benzonitrile -C=N

Draw & name 10 Isomers of C 4 H 7 NO 2

Draw Isomers of C 4 H 6 O 2