NML Bioinformatics Service— Licensed Bioinformatics Tools High-throughput Data Analysis Literature Study Data Mining Functional Genomics Analysis Vector.

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Presentation transcript:

NML Bioinformatics Service— Licensed Bioinformatics Tools High-throughput Data Analysis Literature Study Data Mining Functional Genomics Analysis Vector NTI Advance®

SoftwareLicense type License number GalaxyOpen AccessUnlimited 1524 Partek FlowAnnual/Floating NextbioAnnual/SiteUnlimited BIOBASEAnnual/SiteUnlimited Oncomine*Annual/Named Golden Helix SVS 7**Annual/Floating GenevestigatorAnnual/Named Partek Genomics SuiteAnnual/Floating Ingenuity Pathway AnalysisAnnual/Floating Vector NTI AdvancePerpetual/Floating Total Annual Registered Users * Oncomine was downsized to 2 named users starting FY2014, user growth in 2014 represent the number of consultation requests ** Golden Helix SVS 7 was downsized from 1 floating license to 1 fixed license starting FY2014 and discontinued in FY2015 Cumulative Annual Registered Users of NML Licensed Commercial Bioinformatics Resources

$65,000 $1,870,000 Centralized Licensing Model Delivers Dramatic Cost Saving

Average monthly sessions = 314 Average monthly hours = 323 hr Ingenuity Pathway Analysis USC (Jan Dec.2014)

Average monthly denied sessions = 117 Ingenuity Pathway Analysis Monthly Denied Sessions (Jan Nov. 2014)

Bioinformatics Computing Resources at Norris Medical Library Computer Workstations in Norris Medical Library Hardware: Four Dell Precision T3550/T3660 workstations with 6-core Intel Xeon processors, GB memory Software: Partek Flow, Galaxy, Cistrome, annovar R& Bioconductor, CAP-miRSeq Total Storage: 62 TB (May 2015) Custom Computing Cluster in USC High- Performance Computing Hardware: One head node and 9 worker nodes*. Each with dual processor 6/8-core AMD Opteron 6176 or Intel E5-2650, GB memory. Software: Partek Flow, Galaxy, Cistrome, R& Bioconductor Total Storage: 4 TB You HPC file system File transfer Log on HPC HPC-NML custom condo Submit jobs HPC-NML head node

2014 Next Generation Sequencing (NGS) Data Analysis at NML Bioinformatics Service Galaxy FromTo# Users# Projects# Data Files Total Raw File Size (GB) Estimated Run Time (day) 1/1/201412/31/ Partek Flow FromTo# Users# Projects# Data Files Total Raw File Size (GB) Total Run Time (day) 1/1/201412/31/

NGS Growth in Biomedical Research

Computing Storage Growth at NML Bioinformatics Service