Y-Prize Kick-Off David Hsu Richard A. Sapp Professor of Management The Wharton School

Y-Prize Enabling innovators to commercialize pioneering biomedical engineering technologies

2 approaches to generating venture ideas Start with the problem to be addressed and brainstorm potential solutions Start with the solution or technology to be used and brainstorm potential applications

2 approaches to generating venture ideas Start with the problem to be addressed and brainstorm potential solutions (X-prize) Start with the solution or technology to be used and brainstorm potential applications (Y-prize)

Phase I: Team formation, ideation, concept development, market analysis, feasibility study (due November 6) Phase II: Design, prototyping, developing a business plan (Finals: January 2016) Y-Prize in Biomedical Engineering

Competition Schedule Oct. 12 Tech Briefing, Ideation, and Team Formation Event with Wharton and SEAS faculty Oct. 28 (tentative) Creating Your Proposal Q&A with Wharton faculty and business consultants Nov. 6 Submission deadline. Teams submit 5 min video pitches of their applications Nov. 20Finalists announced. Finalist teams are paired with a tech and business consultant Jan. 2016Grand Finale. Finalists present applications to a panel of judges. Grand Prize: $10,000. $2,500 for each of the 3 finalist teams

Y-Prize in Biomedical Engineering

Judges Dean Miller, President and Chief Executive Officer, Greater Philadelphia Alliance for Capital and Technologies (PACT) Brian Chow, Assistant Professor of Bioengineering, University of Pennsylvania Peter Melley, QED Program Manager, University City Science Center

Judges – Dean Miller Dean Miller is President and CEO of PACT, the region's largest business association focused on emerging growth companies in the technology and healthcare industries. He is also Managing Director for Novitas Capital operating where investment for seed, start-up and early stage technology and life sciences ventures is scarce. Previously, he served as the CFO of Adaptiv Learning Systems, a venture-backed start-up company that was spun out of Penn’s Psychology Department. Dean is also Co-Founder and Vice Chairman of Wharton Private Equity Partners and has served as an adjunct faculty Wharton. He holds a BA in Business Administration and Psychology from Franklin and Marshall College and a Wharton MBA in private Equity. Dean Miller, President and Chief Executive Officer, Greater Philadelphia Alliance for Capital and Technologies (PACT); Private Equity Evergreen; Managing Director, Novitas Capital

Judges – Brian Chow Brian Chow’s laboratory invents new technologies to manipulate and monitor cellular physiology in intact biological circuits. Prior to Penn, he was at Third Rock Ventures, a life sciences venture capital firm, and served on the founding management team of SAGE Therapeutics, a company developing medicines for rare nervous system disorders. He has also held engineering roles at IBM. Brian received his B.S. in Chemistry from Stanford University and his Ph.D. from the MIT Media Laboratory Brian Chow, Assistant Professor of Bioengineering, University of Pennsylvania

Judges – Peter Melley Peter Melley is the Program Manager of QED, a proof-of-concept program and investment portfolio which provides research funding and business guidance to investigators developing high-potential medical technologies in order to attract follow-on investment or expedite a tech- transfer event. Prior to this, Peter worked for two start-ups focusing on business and legal issues. Peter began his career as a corporate attorney at an AmLaw 50 law firm in Washington, DC. Peter holds a BS in Biology for The American University and a MA in Biotechnology and a JD, both from the University of Pennsylvania. Peter Melley, QED Program Manager, University City Science Center

Y-Prize Kick-Off Saikat Chaudhuri Executive Director, Mack Institute for Innovation Management Interim Director, M&T Program Adjunct Associate Professor of Management, The Wharton School

A Central Node in a Knowledge Network 13 The Mack Institute’s mission is to promote thought leadership on innovation management and its application on campus and beyond.

Y-Prize: A Penn Engineering/Wharton Collaboration Mack Institute research priorities focus on study of Innovation Management The institute provides expertise on the challenges of bringing new technologies to market Successful commercialization must be take a cross- disciplinary approach

2015 – 2016 Technology: Biomedical Engineering Penn Engineers are working to tackle some of medicine’s most fundamental challenges, and they’ve invented amazing technologies along the way. The commercialization of these technologies represents the perfect integration of knowledge between Engineering and Medicine and Business. We are excited to offer these three technologies, each of which has the potential to dramatically improve the way we deliver medical care.

2015 – 2016 Technology: Biomedical Engineering Image Registration and Segmentation Brian Avants, Jim Gee, and Paul Yushkevich Enables diverse applications in image/video analysis and processing, ranging from detection and surveillance, to image morphing and motion modeling, to tracking and monitoring of disease and therapy. Microfluidic Fabrication David Issadore An integrated microchip to expand microfluidics to the industrial scale Big Data Analysis Platform Zack Ives and Brian Litt A software environment that rapidly integrates diverse data, networks scientists, facilitates data visualization, analysis, presentation and real time applications at scale.