基隆長庚醫院 食道癌治療小組年度報告 2009/10/02

食道癌治療小組成員 胸腔外科 : 劉會平 胸腔外科 : 陳子平 放射腫瘤科 : 蔡介生 放射腫瘤科 : 陳彥超 放射診斷科 : 陳肇長 核子醫學科 : 詹勝傑 病理科 : 黃成正 胃腸肝膽科 : 胡瀞之 血液腫瘤科 : 王正旭 血液腫瘤科 : 葉光揚 血液腫瘤科 : 賴建宏

Patient characters 117 patients (59 in 2007, 58 in 2008) Male: Female 109 : 8 (55+54 : 4+4 ) SCC: Adeno: other 102 : 8 : 5 (49+53: 4+4: 4+1)

Location of tumor Cx 4 (3+1) U/3 20 (9+11) M/3 68 (36+32) L/3 23 (10+13)

117 patients Stage I : 7 (96=4, 97=3) Stage II A (T2N0, T3N0) 19 (96=8, 97=11) Stage II B (T1n1, T2N1) 8 (96=6, 97=2) Stage III (T3N1,T4Nany) 38 (96=25, 97=13) Stage IV A 8 (4, 4) Stage IV B 27 (9, 18)

Esophageal Cancer Stage0IIIIIIIV*Unk. Case no Total 180 From: year 2000 cancer statistics review of CGMH (N. Taiwan) * Unk. : Unknown

Esophageal Cancer HistologyCase No. Squamous Cell Carcinoma 177 Adenocarcinoma 8 Carcinoma, Others & NOS 9 Malignant Lymphoma 1 Others 9 Total 204 From: year 2000 cancer statistics review of CGMH (N. Taiwan)

Locally advanced (T3N0, T2N1,T3N1) status 與他院比較 At NTUH 97 patients, 2000 ~ 2005 Median age: 56 (range ) Male / Female = 90 / 7 Squamous / Adeno = 92 / 5 Cervical / Upper / Mid / Lower = 8 / 27 / 39 / 23 T3N0 / T2N1 / T3N1 = 8 / 2 / 87 Lin CC, et al. Ann Oncol 2007;18:93-8

Survival ? T4 survival M1a survival M1b survival With-2 nd primary survival

2007 M1b 9/ 59; N1: 43; T4: 12 (PET 22) 2008 M1b 18/ 58; N1: 32; T4: 18 (PET 36) 2007 M1a M1a T1N0M T1N0M0 3

2008 T status on EUS & CT T-EUS vs T-CT EUS 36 attempted, 34 completed CT > EUS: 8 CT < EUS: 9 CT = EUS: 8 EUS endoscopic ultrasound CT computed tomography

2nd primary nd primary 6/ 59 (5 synchronous, 1 HN then eso) nd primary 10/ 58 (6 synchronous, 4 HN then eso) So, 2nd primary 2-year 16/ 117 cases  14% 2nd primary: H&N: 11/ 16 (eso all SCC) HCC: 2/16 (eso all SCC) CRC: 3/ 16 (eso 2 SCC, 1 adeno)

2008 Tx 轉院 7 CCRT: 19 (ITT: 20), ( 3 in LK) OP: 5 CCRT+OP: 10 OP+CCRT:4 Palliative C/T:4 Suportive care:2 ???: 4: 俞春雄 曹英雄 張家榮 許涼一

2007 Tx 轉院 3 CCRT: 26 (ITT: 27), ( 2 in LK) OP: 3 CCRT+OP: 8 (2 CCRT IN LK) OP+CCRT: 9 (6 CCRT IN LK) Palliative C/T: 1 Suportive care: 1 Lost f/u: 1 林春長