Osteoconductive phosphoserine-modified poly(ε-lysine) dendrons: synthesis, titanium oxide surface functionalization and response of osteoblast-like cell.

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Presentation transcript:

Osteoconductive phosphoserine-modified poly(ε-lysine) dendrons: synthesis, titanium oxide surface functionalization and response of osteoblast-like cell lines by S. T. Meikle, G. Bianchi, G. Olivier, and M. Santin Interface Volume 10(79): February 6, 2013 ©2013 by The Royal Society

Physico-chemical characterization of G3 PL-PS dendrons. S. T. Meikle et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

Scanning electron microscopy of (a) unmodified etched TiO2 surfaces and (b) G3 PL-PS- functionalized TiO2 surfaces. S. T. Meikle et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

Surface analysis of TiO2 surfaces. S. T. Meikle et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

MG-63 osteoblast-like cell adhesion after 3 h incubation on (a) tissue culture plastic, (b) unmodified etched TiO2 and (c) PL-PS-functionalized TiO2. S. T. Meikle et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

Osteoblast-like cell proliferation on unmodified etched TiO2 and PL-PS-functionalized TiO2 surfaces. S. T. Meikle et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

SAOS-2 osteoblast-like cell differentiation on unmodified etched TiO2 and PL-PS-functionalized TiO2 surfaces. S. T. Meikle et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society