Lymphoid Tissues Lecture 4, 13/9/2015.

Slides:

Advertisements

Similar presentations

بسم الله الرحمن الرحيم. Cells of the immune system -monocytes/macrophages -granulocytes/polymorphonuclear cells - (PMN) -mast cells -interdigitating.

Advertisements

Chapter 3 Immune System Chapter 3 Immune System (Is)  Immune organs and immune tissues Central immune organs(primary lymphoid organs) Peripheral immune.

A rough guide to the immune system Dr Adrian Palfreeman Senior Clinical Scientist MRC CTU.

1 5/8/2015 Tissues of the Immune Response Tissues of the Immune Response Hugh B. Fackrell Filename:tissuesv7.

I MMUNE SYSTEM ORGANS & CELLS. I – S TEM OR M OTHER CELLS : It’s the place of the origin (Generation of lymphocytes) *found in the fetal liver during.

Lymphocytes and Lymphoid Tissues. Basic Pathway Figure 2-3.

Molecular medicine Immunology 2

16-1 Topics Immunity Lymphoid system Immunity Matures throughout life Has memory – enhanced response to pathogens Vaccination – deliberate exposureto.

Immunology Chapter 3, Lecture 4

LYMPHOID ORGANS The Immune System. Functions of Immune System Has the ability to distinguish ‘self’ from non-self Has the ability to distinguish ‘self’

Immune system Lecture Immune system Innate - non-specific (no immunisation required) o physical barriers (skin, mucosa, cilia) o biological barriers.

20 The Lymphatic System and Lymphoid Organs and Tissues.

Types of lymphoid tissues A- Generative organs or primary lymphoid organs The sites for cell proliferation and maturation Such as Bone marrow and thymus.

INTRODUCTION TO IMMUNITY IMMUNOLOGY LECTURE 1 Dr Jayne Powles.

Human immune system. By as. E.V. Pokryshko Medical biology, microbiology, virology, immunology department.

The Lymphatic System. Functions Of The Lymphatic System Transport Excess Interstitial Fluid Back To Bloodstream Transport Dietary Lipids House Lymphocytes.

Lymphatic system A series of highways training centers & checkpoints for our immune cells.

Organization of the lymphoid organs and tissues

Lymphoid Tissues and Organs: - Leukocytes may be distributed in the body as: 1-Single cells in tissues and circulation. 2-Lymphoid accumulations (Peyer’s.

Aim: How does our immune system protect against antigens of pathogenic organisms? HW 22 Read Ch 40 pages 1028 – 1048 Pg 1034 vocabulary Pg 1050 Thinking.

Lymphoid Tissue Forms the basis of the immune system of the body Forms the basis of the immune system of the body Lymphocyte, the principal cell of lymphoid.

Unit 1Nature of The Immune System Part 4 Specific Immunity Terry Kotrla, MS, MT(ASCP)BB.

Lymphoid System T and B Cell Development Prof. Dr. Zahid Shakoor MBBS, Dip. Med. Immunology (UK), Ph D (London) King Saud University.

 The thymus and bone marrow are the primary lymphoid organs in mammals.  T and B lymphocytes with diverse antigen receptors are produced in these organs.

 The immune and lymphatic systems are two closely related organ systems that share several organs and physiological functions.  The immune system is.

Immunology The study of the organs, tissues and cells that create the body’s fight against disease. Immunity – ability to stop a pathogen from establishing.

Lymphoid System and Immune cells Immunology Unit Dept. of Pathology.

The Immune System The Anatomy of the Immune System.

Chapter III General introduction of immune system.

خلايا الجهاز المناعي Cell and Organs of the Immune System تنشأ خلايا الجهاز المناعي من نخاع العظام Pluripotent haemopoietic stem cells خ يا الجذعية المكونة.

Mrs. Dalia Kamal Eldien MSC in Microbiology Lecture NO 12.

Aims State the normal functions of the immune system.

Advanced Biology Chapter 21 Lymphatic System.  Arteries  lymphatic vessels (lymphatics)

Chapter III The tissues and organs of immune system.

Nada Mohamed Ahmed, MD, MT (ASCP)i. Nada Mohamed Ahmed, MD, MT (ASCP)i.

Macrophages -Alveolar macrophages in the lung -Histiocytes in connective tissues -Kupffer cells in the liver -Mesangial cells in the kidney -Microglial.

LYMPHOID TISSUE Lymphocyte. LYMPHOID TISSUE A) Diffuse lymphoid tissue B) Encapsulated lymphoid organs: 1- Lymph nodes. 2- Spleen. 3- Tonsils (are incompletely.

Immune-Lymphatic System – 2 Lymphatic Organs

NAJRAN UNIVERSITY College of Medicine NAJRAN UNIVERSITY College of Medicine Microbiology &Immunology Course Lecture No. 15 Microbiology &Immunology Course.

ORGANS OF THE IMMUNE SYSTEM LYMPHOID ORGANS ORGANIZATION AND STRUCTURE OF THE IMMUNE SYSTEM GENERATION AND MIGRATION OF CELLS OF THE IMMUNE SYSTEM LYMPHOCYTE.

Types of lymphoid tissues A- Generative organs or primary lymphoid organs The sites for cell proliferation and maturation Such as Bone marrow and thymus.

Lymphatic Organs Primary lymph organs are the bone marrow and thymus. – Sites where stem cells divide and become immunocompetent (capable of mounting an.

Innate and Adaptive Immunity

Chapter 20: Lymphatic System. Lymphatic System: Overview Lymphatic vessels Lymphoid tissues and organs Returns interstitial fluid and leaked plasma proteins.

IMMUNE SYSTEM Shiping Ding ( 丁世萍 ), Ph. D School of Medicine, Zhejiang University address:

Structure of Lymphoid System Components. FUNCTIONS OF THE IMMUNE SYSTEM PROTECTION AGAINST FOREIGN INVADERS INTO BODY PRODUCE / PROTECT GERM FREE ENVIRONMENT.

بسم الله الرحمن الرحيم. LYMPHOID TISSUE Objectives: By the end of the lecture, the student should describe the microscopic structure of the following.

Immune-Lymphatic System – 2 Lymphatic Organs ANHB 2212 – 2006 – Week 9 Avinash Bharadwaj.

LYMPHATIC SYSTEM Nada AL-Juaid. lymphatic system  The lymphatic system is part of the circulatory system,circulatory system.

Human immune system CELLS COOPERATION IN IMMUNE RESPONSE.

Cells, Tissues, & Organs of The Immune System Pin Ling ( 凌斌 ), Ph.D. ext 5632; References: 1. Male D., J. Brostoff, D. B Roth,

Web: Downloads Login: student Password: download Materials for the lectures and seminars can be downloaded:

LYMPHOID TISSUE Objectives: بسم الله الرحمن الرحيم

Immunology 오 상택.

Kuby Immunology, 7e: Chapter 2

IMMUNOLOGY AND THE IMMUNE SYSTEM

Immune system organs & cells

T and B Cell Development

Histology of Lymphoid tissue

GENERAL IMMUNOLOGY PHT 324

Lymphoid Tissues and Organs:

Overview B cell development T cell development Topics 11/7/2018

Cells and organs of Immune system

The Lymphatic System 20.

Chapter 10 Immune system.

Lymphatic System.

Peripheral (Secondary) Lymphoid Organs

IMMUNOLOGY AND THE IMMUNE SYSTEM

Presentation transcript:

Lymphoid Tissues Lecture 4, 13/9/2015

What are lymphoid tissues Organised tissues containing immune cells. Where cells develop and mature, (primary/central LT). Where lymphocytes interact with non-lymphoid cells, (secondary/peripheral LT). Where cellular interactions and then initiation of adaptive immune responses

Major lymphoid organs and tissue Primary lymphoid tissues: (Central) Bone marrow: B cells maturation, Myeloid cells, NK. Thymus: T cells maturation Secondary lymphoid tissues: (Peripheral) Lymph nodes Spleen Mucosal lymphoid tissues (adenoids, tonsils, Peyer’s patches etc).

What do they do? Most important part of the immune system. Immune cell development and maturation. Gathering and destroying infectious agents by mounting immune responses.

Bone Marrow Origin of immune system cells Network of stromal epithelial cells Haematopoietic stem cells Growth factors regulate cell proliferation and differentiation B cell maturation

Haematopoietic stem cells الخلايا الجذعية المكونة للدم Three main lineages: Erythroid: Red blood cells Myeloid: Granulocytes,Megakaryocytes Lymphoid : lymphocytes, NK cells

Haematopoiesis آلية تكوين الدم

Bone Marrow Birds bursa of Fabricius (B cell maturation) Mammals B.M. (B cell maturation) Except: Cattle + Sheep Payer's Patch (B cell maturation) Rabbit Appendix

Thymus

Features and Functions 1 Most active in childhood, atrophies with age. Composed of 1- cortex (immature T cells are many) 2- medulla (mature T cells are few) Medulla contains Hassall’s corpuscles (thymic corpuseles). T cell maturation

Features and Functions 2 Secretes thymic hormones to attract T cell and promote their differentiation. Rich in epithelial cells. Selects against self-reactive T cells.

Cells of the Thymus

Thymus: Hassall’s corpuscle Unique to thymus Clusters of epithelial cells ? Remove apoptotic thymocytes Small spherical bodies in the medulla, composed of epithelial cells arranged around clusters of degenerating lymphocytes and macrophages.

Tissues of the adaptive immune response. Summary 1: Tissues of the adaptive immune response.

Cells of the Adaptive Immune System Summary 2: Cells of the Adaptive Immune System B cells Bone marrow Ab production T cells Thymus CD4+ helper cells (Th1 and Th2) stimulate responses CD8+ Cytotoxic cells Kill infected cells

Any Question?