Comparison of Ropivacaine and Bupivacaine Toxicity in Human Articular Chondrocytes by Samantha L. Piper, and Hubert T. Kim J Bone Joint Surg Am Volume.

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Comparison of Ropivacaine and Bupivacaine Toxicity in Human Articular Chondrocytes by Samantha L. Piper, and Hubert T. Kim J Bone Joint Surg Am Volume 90(5): May 1, 2008 ©2008 by The Journal of Bone and Joint Surgery, Inc.

Bar graph showing the percentage of live chondrocytes within cartilage explants twenty-four hours after a thirty-minute treatment with 0.9% normal saline solution, 0.5% ropivacaine, or 0.5% bupivacaine. Samantha L. Piper, and Hubert T. Kim J Bone Joint Surg Am 2008;90: ©2008 by The Journal of Bone and Joint Surgery, Inc.

Fluorescence microscopy images of human articular cartilage explants stained with 1-μM calcein AM and 1-μM ethidium himodimer-1 twenty-four hours after a thirty-minute treatment with (A) 0.9% normal saline solution, (B) 0.5% ropivacaine, or (C) 0.5% bupivac... Samantha L. Piper, and Hubert T. Kim J Bone Joint Surg Am 2008;90: ©2008 by The Journal of Bone and Joint Surgery, Inc.

Bar graph illustrating chondrocyte viability in monolayer tissue culture twenty-four hours after a thirty-minute treatment with 0.9% normal saline solution, 0.5% ropivacaine, or 0.5% bupivacaine. Samantha L. Piper, and Hubert T. Kim J Bone Joint Surg Am 2008;90: ©2008 by The Journal of Bone and Joint Surgery, Inc.