Philips 3T Achieva Visual Cortex fMRI brain scan BOLD

MONK RF signal audio tone juice controller juice dispenser solenoid EMG neuron AP fMRI BOLD visual task IR camera CPU Cortex/LabView monitor

Non-human primate of choice: anatomical & physiological likeness ease of maintaining & breeding in captivity No harm / minimize discomfort IACUC (Institutional Animal Care and Use Committee) IRB (Institutional Review Board) approval Ethics Research Training (exam # )

Mark Pinsk (Princeton, 2004) Wim Vanduffel (MGH/Belgium, 2001)

Improvements: mechanical design, materials selection, audio reinforcement, component integration

Materials: Peek & polycarbonate Costs: mechanical ($3,000) {+ functional ($100k/P.O.)} CAD software: Vector Works ProE Solid Works Use: joint Psych & VUIIS; frequency; 11 monkeys Crist Instruments

Mechanical design drawings Van Duffel designs Head movement prediction w/ CAD & bone properties to create optimally stable head restraint Meeting with Bruce design revisions Pinsk Mock scanner environment Functional components: QFDs & selection

Limin Chen (Psych) – rhesus & fMRI Ken Wilkens (VUIIS) – MR engineer Bruce Williams (Psych) – machining Calum Avison (VUIIS) – primary investigator

MonthGoal November 2005Identify project goals, parameters and resources December 2005Finish initial research; Create design approach January 2006Finalize design approach; Begin prototyping February 2006Finalize prototype; Begin prototype testing March 2006Modify prototype as necessary; Re-test (& re-modify) April 2006Finalize prototype; Prepare/present paper and poster