Sex hormones, heart, kidney

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Presentation transcript:

Sex hormones, heart, kidney

Sry (TDF) Anti Muellerian hormone

MaleTestisAdrenal Peripheral conversion Testosterone95<1<5 5α-DHT20<180 Androstenedio ne 20<190 DHEA2<198 DHEA-S<1090- FemaleOvaryAdrenal Peripheral conversion Testosterone5–25 50–70 5α-DHT--100 Androstenedio ne 45–6030–4510 DHEA2080- DHEA-S<5>95-

Pathology Amenorrhea – Primary & secondary Infertility Menopause & Andropause

CVS and renal hormones Cardiovascular systemKidney HormoneFunctionHormoneFunction Atrial natriuretic peptide (ANP) ↑ Filtration rate / ↓Na + reabsorption Renin (enzyme) ↑ Angiotensin- aldosterone system Endothelins (ET-1, ET-2, ET-3) Vasoconstriction / ↑NOProstaglandins↓ Na + reabsorption Nitric oxide (NO)VasodilatationErythropoietin ↑ Erythrocyte production 1,25 (OH) 2 vitamin DCalcium homeostasis Prekallikreins↑ Kinin production

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