Chapter 14 DNA: The Molecule of Heredity
The Beginning of the Era 1800s – Scientists have discovered that traits are passed down through generations The discrete units are called genes Genes are associated with a thread- like material in nuclei called chromosomes Chromosomes are made of nucleic acids and proteins
Which chemical is responsible for the passage of traits?
Fredrick Griffiths 1920s Utilizing Streptococcus pneumoniae Strain differences “Transforming Factor”
Avery, MacLeod, and McCarty 1940s Reworked Griffith’s experiment Utilized technology not available to Griffith Purified classes of macromolecules
DNA is the carrier of heredity!
How does DNA accomplish transfer of information?
DNA Bases
Key Evidence – X-Ray Data
The Players in Discovering the Structure Erwin Chargaff Linus Pauling Maurice Wilkins and Rosalind Franklin James Watson and Francis Crick
The Double Helix
Replication
Chapter 10 Transcription and Translation
RNA
Genetic Code
Translation
Translation (cont.)
Flow of Information
Mutation