Regulating the Cell Cycle and Cancer Ms. Cohen

How carefully do cells divide? Quite controlled Some cells divide at different rates –Cells that divide seldom: _______________ –Cells that divide often: _______________

Controls on Cell Division Cells will grow if given ample _______________ They stop when they reach other ______ What happens when you get a cut?

Cell Cycle Regulators Cyclins and proteins: _____________________________

Regulators ___________ regulators are proteins that respond to events inside the cell. –Allow cell to proceed when certain processes have occurred inside. ___________ regulators are proteins that respond to events outside the cell. –Direct cells to speed up or slow down the cell cycle.

Uncontrolled Cell Growth Cancer cells do not respond to the signals that regulate the growth of most cells. Divide ___________ Form masses called __________ Cancer cells may break loose from tumors and spread. Breast cancer cells forming in a duct

What causes cancer? External factors: _____________ Internal factors: _____________

P53 gene on Chromosome 17 Gene therapy is being used to kill cancer cells when p53 does not work to kill cells.