Manaaki Tangata Taiao Hoki protecting people and their environment through science Specialist Science Solutions NIC’s Pandemic influenza response and activities.

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Presentation transcript:

Manaaki Tangata Taiao Hoki protecting people and their environment through science Specialist Science Solutions NIC’s Pandemic influenza response and activities in New Zealand Dr. Sue Huang Head, WHO National Influenza Centre Institute of Environmental Science and Research Wellington, New Zealand The 3 rd WHO National Influenza Centre meeting, Beijing August 2009

© ESR 2006 Outline Pandemic influenza & seasonal influenza situation NIC’s response & activities during early containment phase NIC’s response & activities during late containment phase NIC’s response & activities during management phase

© ESR 2006 Epidemic curve of pandemic (H1N1) 2009 cases As of 2 August: Total cases: hospitalised 109 pneumonia 25 ARDS 39 fatal cases reported with10 being confirmed to have pandemic virus as the primary cause

© ESR 2006 Weekly ILI consultation rates in 2009

© ESR 2006 Weekly ILI consultation rates,

© ESR 2006 Influenza strain surveillance

© ESR 2006 NIC’s response & activities during early containment phase (25 April-Mid May) NIC developed a nested PCR and sequencing method for NA gene with good sensitivity: confirmed 3 pandemic (H1N1) 2009 cases NIC did a contingency plan and identified 5 bottle necks: test result reporting; specimen reception; automation; testing algorithm; technical staff

© ESR 2006 NIC’s response & activities during late containment phase (Mid May-21 June 2009) Highest sample volume: - For a week: ~1000 samples - For a day: ~350 samples High political commitment: mobilize resources from MAF IDC, AgResearch, ESR CD group; Test for Pacific Island countries: Cook Island, Samoa, Togan

© ESR 2006 NIC’s response & activities during management phase (22 June-present) Viral culture and antigenic typing Tamiflu resistance monitoring Investigation of coinfection of pandemic A(H1N1) and seasonal A(H1N1) cases Full genome sequencing for fatal and ICU cases Potential sero-survey

© ESR 2006 Influenza VirusSeasonal AH1N1Novel AH1N1 Year Number of viruses Mean IC50 * Std. dev Min IC Max IC Oseltamivir resistance monitoring

© ESR 2006 Thank you