Dinah Callender, RN The Pennsylvania State University

 Describe the lab-on-a- chip  Describe the hardware used in the trend  Review Software  Define Axioms  Review Criteria  Describe Advantages and Disadvantages

 Ethics and Legal issues  Describe informatics nurse using the chip  Summarize the lab on a chip

 Instrument that integrates one or several laboratory functions  Only millimeters to centimeters in size

 Few drops of blood needed to function  Invented to perform blood analyses

 Laptop or PDA  Semiconductor Chip  Special Camera  Handheld device controller

 Semiconductor chip  Made of  Silicon  Glass  Plastic  Paper

Some of the software used in the chips created by Agilent Technologies are:  Compliance solution  RNA Solution  Mass spectrometry software  2100 Expert Software

 2100 Expert Software for the Agilent 2100 Bioanalyzer -offers powerful data evaluation tools for all available assays - automatic and manual integration - smear analysis and many assay-specific tool.

 Axiom 1- meets goal of user  Axiom 2 the software allows for evaluation and correction  Axiom 3- needs to be determined.

 Designed to collect patient data  Improves care by making data accessible  Patient-focused

 This is a clinical information system  Used by physicians, nurses, and pharmacist  Enables documentation  The Configuration utilized is point of care  Data standard used is Healthlevel 7 (HL7)  Disease and Procedure Classification System (Northrop Grumman, 2010)

 Nursing practice standards classification scheme

 A decrease or no human mistakes  Can find bacteria, viruses, and cancers  Can extract DNA from cells  Cost effective  Small amount of blood needed

 Chip is new on the scene  Not yet mature  People may be reluctant

 Lab on a chip utilizes wireless communication  Utilizes expert systems to develop diagnoses  Raises concern about privacy and legal responsibility  Personal health information widely accessible

Beginning nurse would be able to :  Retrieve information  obtains results from patient monitoring system  Understands lab on a chip’s limitations Experienced nurse  Troubleshoots problems  Places monitoring systems

Informatics nurse specialist  Will provide training programs  Foresees impacts on staff and patients  Makes lab on a chip user friendly Informatics Innovator  Develops sample trials  Does advanced analysis

 Provides the education on how to use the chip  Show ways to troubleshoot any problems  Research to create new knowledge  Utilizes tools to maintain data integrity

 A mini-lab on a polymer chip  Uses small volumes of blood/ fluid  Fluids moved by pressure through channels  Used for mixing, dilution, staining  Detection on single integrated systems

 Agilent Technologies.(July, 2009) Expert Software. Retrieved on March17,2010,from labonachip/2100bioanalyzer/smallrnaassay/  CBC News (2009, Oct.7). Breast cancer ‘lab on a chip’ developed. Retrieved on March17,2010, fromhttp:// ast-cancer-chip. ast-cancer-chip  Northrop Grumman (2010). Clinical Information System. Retrieved on April 17, 2010, from on/health_it/markets/health_cis/index.html

 Insight:Lab on a chip (July 26, 2006). Nature. Retrieved on March 17, 2010, from a.html a.html  Lab-on-a-chip. Retrieved March 17, 2010, from  Societal and Ethical Interactions with Nanotechnology (SEIN)-An Introduction (April, 2005). SOCIETY ETHICS_BAIRD VOGTTOSEND[1].Retrieved April 18,2010,from