This article and any supplementary material should be cited as follows: De Kooning M, Daenen L, Roussel N, Cras P, Buyl R, Ickmans K, Struyf F, Nijs J.

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This article and any supplementary material should be cited as follows: De Kooning M, Daenen L, Roussel N, Cras P, Buyl R, Ickmans K, Struyf F, Nijs J. Endogenous pain inhibition is unrelated to autonomic responses in acute whiplash-associated disorders. J Rehabil Res Dev. 2015;52(4):XX–XX. Slideshow Project DOI: /JRRD JSP Endogenous pain inhibition is unrelated to autonomic responses in acute whiplash-associated disorders Margot De Kooning, MSc; Liesbeth Daenen, PhD; Nathalie Roussel, PhD; Patrick Cras, PhD, MD; Ronald Buyl, PhD; Kelly Ickmans, PhD; Filip Struyf, PhD; Jo Nijs, PhD

This article and any supplementary material should be cited as follows: De Kooning M, Daenen L, Roussel N, Cras P, Buyl R, Ickmans K, Struyf F, Nijs J. Endogenous pain inhibition is unrelated to autonomic responses in acute whiplash-associated disorders. J Rehabil Res Dev. 2015;52(4):XX–XX. Slideshow Project DOI: /JRRD JSP Aim – Compare autonomic response to painful stimuli between patients with acute and chronic whiplash-associated disorder (WAD) and healthy controls. – Examine role of autonomic nervous system for explaining inefficient endogenous pain inhibition in acute WAD. Relevance – Patients with acute WAD demonstrate inefficient endogenous pain inhibition and may experience dysfunction in autonomic nervous system reactivity to pain.

This article and any supplementary material should be cited as follows: De Kooning M, Daenen L, Roussel N, Cras P, Buyl R, Ickmans K, Struyf F, Nijs J. Endogenous pain inhibition is unrelated to autonomic responses in acute whiplash-associated disorders. J Rehabil Res Dev. 2015;52(4):XX–XX. Slideshow Project DOI: /JRRD JSP Method Evaluate autonomic nervous system at rest and during painful stimuli. – 17 patients with acute WAD. – 30 patients with chronic WAD. – 31 healthy controls. Skin conductance and heart rate variability (HRV) parameters monitored continuously during conditioned pain modulation.

This article and any supplementary material should be cited as follows: De Kooning M, Daenen L, Roussel N, Cras P, Buyl R, Ickmans K, Struyf F, Nijs J. Endogenous pain inhibition is unrelated to autonomic responses in acute whiplash-associated disorders. J Rehabil Res Dev. 2015;52(4):XX–XX. Slideshow Project DOI: /JRRD JSP Results Significant autonomic response to pain present for skin conductance and 2 HRV parameters in all experimental groups. Interaction effect of skin conductance response to pain but not in HRV responses in any group. No significant correlations between pain, pressure pain thresholds, pain inhibition, and any autonomic parameters in patients with acute WAD.

This article and any supplementary material should be cited as follows: De Kooning M, Daenen L, Roussel N, Cras P, Buyl R, Ickmans K, Struyf F, Nijs J. Endogenous pain inhibition is unrelated to autonomic responses in acute whiplash-associated disorders. J Rehabil Res Dev. 2015;52(4):XX–XX. Slideshow Project DOI: /JRRD JSP Conclusion This study refutes autonomic dysfunction at rest and in response to pain in acute WAD. Dysfunctional conditioned pain modulation appears unrelated to autonomic responses to pain.