ISE789 Biomedical Product Engineering Dr. Richard A. Wysk Spring 2010

Agenda Policies - This is an engineering course, I do expect you to act like engineering students. Independent, diligent, creative,... Engineering ethics There is no cure for improper behavior

Overview What we will we be doing? –ISE789 is new (sort of the 1 st offering), amorphous and should be lots of fun. It will be the most exciting class that you take. For five plus years, I have been working on medical products development. This area is VERY different than traditional durable goods. Hopefully by the end of the semester, you will see how different commercial and medical systems can be. –Biomedical systems is a difficult topic touching: biology, anatomy, biomechanics, and every aspect of engineering. People do not understand how Biomedical engineering systems fit together. This is the focus of ISE789!

Development activities Course materials have been developed and need to be tested. You will be the beta testers. Active, collaborative learning will be the educational focus for the course. I am looking for feedback in this area.

TEXT Building a Better Delivery System: A New Engineering/Health Care Partnership Proctor P. Reid, W. Dale Compton, Jerome H. Grossman, and Gary Fanjiang, Editors, Committee Engineering and the Health Care System, National Academy of Engineering, Institute of Medicine, ISBN: , 276 pages

Once in a semester opportunity We will have 3-4 Position Papers during the semester. –From NAP text –You can volunteer for a particular paper or be assigned as the topics get consumed. –4-6 people per position (FIFO) –It will be a lot of work but fun as well

Introduction What is a “Biomedical system”? Interactions of many processes (biological, chemical and mechanical), products and design decisions made in the creation of a medical product or delivery of a medical process/treatment.

Vocabulary Glossary of terms –Pathogens, bacteria, virus, fungus, biomechanics, Healthcare delivery,...

Sizes of things Microbes for being small, span a large range of sizes from the T4 virus that are 0.02 µm to giant bacteria larger than 700 µm.

Goal and Objective GOAL – Provide industrial/systems engineers with a basic understanding of medicine and medical device requirements. OBJECTIVE -- reduce time for service, increase quality, reduce cost, and operate in a tight capital environment

Questions?!? I expect to learn as much from you as you do from me. I want this to be fun! Respect and professionalism.

Purpose To identify the opportunities and challenges for conducting ISE research in healthcare.

“Drug-resistant infections kill more Americans than AIDS and breast cancer combined.” $30 billion Cost of hospital/health care associated infections. 1.7 million Patients get health care associated infections. 100,000 Annual deaths from hospital infections. June 19, 2006

Medical Devices and Applications March 24, 2006 (Chicago) -- The number of total knee replacements performed in the U.S. will leap by 673% -- reaching 3.48 million -- by the year 2030, according to a new study presented at the 73rd annual meeting of the American Academy of Orthopaedic Surgery in Chicago. Hip replacements will increase by 174% to 572,000 by 2030, according to the new findings, which are based on historical procedure rates from 1990 to 2003, and on population projections from the U.S. Census Bureau.

Veterinary Applications Kentucky Derby winner Barbaro suffers a fractured leg and develops a serious infection after surgery with implanted plate and screws. Fractured leg Implants that spawned infection

US Demographics Americans 60 or older constituted 16.7% of the population in This is projected to grow to 23.8% in Source: UN World Population Report

U.S. Healthcare Spending is “Booming.” 78 million baby boomers started turning 60 this year Armed with more information and “healthcare activism” Ads target lifestyle conditions, driving Rx Advanced technology costs $$$ and requires engineering (MRI, stenting, etc.) (innovator’s dilemma)

What U.S. healthcare network is the benchmark for patient safety and treatment?

Business Week

Health IndicatorVA Score National Sample Overall67%51% Chronic care7259 Lung disease6959 Diabetes7047 Preventive care6444 Source: Business Week , from Rand Corp. study of treatment provided against national standards.

Test Your Healthcare Knowledge Do the ABC News quiz http://abcnews.go.com/WNT/popup?id=

Note: First response is prechecked, but not necessarily correct.

True.

Summarizing the Sobering Stats. 46 million uninsured (1 in 6 Americans) Cost of $25+ billion/yr 100,000 die from medical error each year

U.S. vs. the World Of 25 industrialized countries –U.S. spends $6,100 per capita –Others average $2,500 per capita –U.S. is 25 th in life expectancy –Healthcare is 1/6 of GNP (4x defense) –Not correlated with income ABC News. “U.S. Healthcare Could Learn From Rest of World.” Report aired 9/21/06. (The Century Foundation citing a joint US-British study).

“ Some grocery stores have better technology than our hospitals and clinics.” —Tommy Thompson, former HHS Secretary Source: Special Report on technology in healthcare, U.S. News & World Report

Engineering and Medicine

How does this work?

Summary We are at a critical state for healthcare. Good engineering and business practice is required. Complex system. –Bio, mechanical, financial –Morale, religious, …