Human GeneticsHuman Genetics Monica Starbinski Greer Manton Sydney Gilbert Period 2.

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Presentation transcript:

Human GeneticsHuman Genetics Monica Starbinski Greer Manton Sydney Gilbert Period 2

Pedigrees Monica Starbinski Key – -Male(affected) - Male (normal) -Female (affected) - Female (normal) - Heterozygous for recessive allele Generation 1 Generation 2 Generation 3

Autosomal Recessive DisordersAutosomal Recessive Disorders Tay-Sachs Disease Cystic Fibrosis Albinism The disorder is present. Phenotype ratio – 1 has disease : 3 do not Percentage – 25% have disease, 75% dont Genotype ratio – 1 AA : 2 Aa : 1 aa Percentage – 25% AA, 50% Aa, 25% aa

Autosomal Dominant Disorders / TraitsAutosomal Dominant Disorders / Traits Huntington’s Disease Widow’s Peak Hairline Free/Hanging Earlobes Phenotype ratio – 3 have disease : 1 does not Percentage – 75% have disease, 25% dont Genotype ratio – 1 GG : 2 Gg : 1 gg Percentage – 25% GG, 50% Gg, 25% gg The disorder is present.

Current Event on Human GeneticsCurrent Event on Human Genetics  /title/Tracing_Jewish_roots Greer Manton

Codominance Genotype Ratio: 1 A1A1 : 2 A1A2 : 1 A2A2 Percentage: 25% A1A1, 50% A1A2, 25% A2A2 Phenotype Ratio: 1 Purple : 2 Red : 1 Yellow Percentage: 25% Purple, 50% Red, 25% Yellow Homozygous Heterozygous Roan Cattle RR’ Flower R’R R RR’RR R’R’RR’ Greer Manton

Multiple AllelesMultiple Alleles Genotype Ratio: 1 TTWW : 3 TTWw, 2 TtWW : 4 TtWw, 2 Ttww : 1 ttWW, 2 ttWw : 1 ttww Percentage: 6.25% TTWW, 18.75% TTWw, 12.5% TtWW, 25% TtWw, 12.5% Ttww, 6.25% ttWW, 12.5% ttWw, 6.25% ttww TtWw x TTWw Dihybrid Haemolytic Anaemia Greer Manton

Sex-linked DisordersSex-linked Disorders Down Syndrome Color Blindness Hemophilia XXXY XX’X’Y X Y X X’ Genotype Ratio: 1 XX; 1 XY; 1 XX’; 1 X’Y Phenotype Percentage: 25% XX; 25% XY; 25% XX’; 25% X’Y Sydney Gilbert

Questions!  1: What is the chance that a mother can pass on the sex linked gene of color blindness?  2: What is bound to happen when a pink flower is crossed with a white flower and results in codominance?  3: If you are albino, what type of dominance do you have?  4: If you possess attached earlobes, what type of dominance is it? Sydney Gilbert