GH Treatment in Children in Remission from Leukaemia and Lymphoma in KIGS Nikolaus Stahnke KIGS 10 Year Book, 1999

N Stahnke - KIGS 10 Year Book, 1999 Treatment groups of patients treated for acute lymphoblastic leukaemia (ALL) TBI, total body irradiation

N Stahnke - KIGS 10 Year Book, 1999 Characteristics of patients with acute lymphoblastic leukaemia (ALL) ALL, acute lymphoblastic leukaemia; TBI, total body irradiation; MPH, mid-parental height; SH, sitting height; LL, leg length; BMI body mass index

N Stahnke - KIGS 10 Year Book, 1999 Growth response in KIGS patients with acute lymphoblastic leukaemia (ALL) during the first year of GH treatment compared with first-year height velocity predicted for children with idiopathic GHD Predicted height velocity for the first treatment year (cm/year) Studentised residuals

N Stahnke - KIGS 10 Year Book, 1999 Height velocity of patients who underwent cranial irradiation, cranial irradiation plus total body body irradiation and craniospinal irradtion for leukaemia and subsequent GH therapy Cranial irradiation ( ), cranial irradiation plus total body irradiation (TBI) ( ) and craniospinal irradiation ( ) Height velocity (cm/year) Duration of therapy (years) X + SE

N Stahnke - KIGS 10 Year Book, 1999 Patients with acute lymphoblastic leukaemia (ALL) at the end of GH treatment TBI, total body irradiation; MPH, mid-parental height; SH, sitting height; LL, leg length; BMI, body mass index

N Stahnke - KIGS 10 Year Book, 1999 Response to GH treatment of the total group of acute lymphoblastic leukaemia (ALL) patients, patients treated with cranial irradiation and with craniospinal irradiation 0, prior to start of GH therapy; FH, end of GH therapy; HT, height; MPH, mid-parental height;, difference; SH, sitting height; LL, leg length Height (SDS) ALL: Total group ALL: Cranial irradiation ALL: Craniospinal irrad HT HT-MPH  SH-LL HT HT-MPH  SH-LL HT HT-MPH  SH-LL 

N Stahnke - KIGS 10 Year Book, 1999 Characteristics at start of GH treatment of patients with acute myeloid leukaemia and non-Hodgkin lymphoma MPH, mid-parental height; SH, sitting height; LL, leg length; BMI body mass index

N Stahnke - KIGS 10 Year Book, 1999 Height velocity (cm/year and SDS for chronological age) and height SDS for chronological age in patients with acute acute myeloid leukaemia and non- Hodgkin lymphoma receiving GH treatment AML ( ), NHL ( ) Duration of therapy (years) Height velocity for chronological age (SDS) Height for chronological age (SDS) Height velocity (cm/year)

N Stahnke - KIGS 10 Year Book, 1999 Characteristics of patients with acute myeloid leukaemia and non-Hodgkin lymphoma at the end of GH treatment