Echinococcosis ( 棘球蚴病） 组员：冯顺意 黄敬贤 龙佳

Echinococcosis ( 棘球蚴病 ) Echinococcus granulosus （细粒棘球绦虫） Hydatid( 棘球蚴 ) It is a zoonotic disease （动物传染病） affecting mainly various species of livestock and humans. It causes great economic losses in animal husbandry

Morphology Echinococcus granulosus ( 细粒棘球绦虫 ) Hydatid ( 棘球蚴 )

Echinococcus granulosus ( 细粒棘球绦虫 ) Definitive host: dog 、 wolf 、 fox Site: small intestine

Hydatid ( 棘球蚴 ) Intermediate host:cattle 、 goat and sheep 、 pig 、 horse 、 camel ， wildlife and humans Site: liver 、 lung

Life cycle

Epidemiology Cosmopolitic distribution （世界性分布） High infection rate in sheep （绵羊感染率 最高） E. granulosus （细粒棘球绦虫） and E. multilocularis （多房棘球绦虫） can infect human Strong resistance of egg

Sympotoms and Lesions Harm the human body and animal body mainly by mechanical damage Hydatid Oppression tissues and organs around it Tissue 、 cell atrophy （ 萎缩）, necrosis （ 坏死）, Hydatid fluid leakage （棘球蚴液渗出） Toxicity or allergic reaction Continued growth

腹部包虫病患者腹部包虫病患者

Section of sheep liver showing fertile Hydatid cysts

DIAGNOSIS Clinical symptoms （临床症状）： a slow-growing tumor accompanied by eosinophilia( 嗜酸性粒细胞增多 ). Intradermal test( 皮试 ) with Hydatid fluid. Pulmonary cysts （肺囊肿） and calcified cysts （钙化的 包囊） can be visualized using x-rays(X 光透视 ). Immunological methods: IHA, ELISA, ABC- ELISA ( 亲和素生物素酶免疫吸附试验 ), E-CIEP ( 酶标 记对流免疫电泳 ), etc

TREATMENT Dogs: Can use praziquantel （吡喹酮）. After treatment it is advisable to confine dogs for 48 hours to facilitate the collection and disposal of infected faeces. Sheep, yak and cattle: Can use albendazole ( 丙硫咪唑 ): 90 mg∕kg （连服 2 次）,and praziquantel ( 吡喹酮 ):25~30 mg∕kg. Humans: Surgical excision （外科切除） of hydatid cysts although there is a risk of re-development of released daughter cysts （子囊）. Can use mebendazole （甲苯咪唑）, albendazole （丙硫咪唑） and praziquantel （吡喹酮）.

Prevention Ban to feed dog with infected organs Deworming of dogs Maintain the barn, feed, water sanitation, prevention of canine fecal contamination For us,pay attention to personal hygiene （个人卫生） Avoiding contact with infected dogs

谢 谢！