Cancer Disparities Research Partnership (CDRP): Linking University & Community Radiation Oncology to Improve Cancer Outcomes Patrick D. Maguire, M.D. New.

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Presentation transcript:

Cancer Disparities Research Partnership (CDRP): Linking University & Community Radiation Oncology to Improve Cancer Outcomes Patrick D. Maguire, M.D. New Hanover Radiation Oncology Wilmington, NC

CDRP: Partnerships in Radiation Oncology The Problem –Clinical Trial Enrollment –University vs. Community The CDRP Solution –Long-lasting Relationships –TELESYNERGY ®

Clinical Trial Enrollment: Failing our patients, both current & future? Pediatric vs. Adult – ~50% vs. <5% (DHHS, 2003) Majority vs. Underserved –Low minority enrollment (0.05 x 0.1) –Are trial endpoints representative?

University vs. Community Radiation Oncology: Ivory Tower vs. The Dark Side!

“Make Love, Not War” UNIVERSITY: Research, lab & clinic Focused expertise New technologies Clinical trials COMMUNITY: Large n (patients) Convenience Cultural bonds Clinical trials less common

Essentials of A Successful Relationship Mutual contribution & care Mutual benefit Marriage: love & effort!

The CDRP Solution to The Clinical Trials Problem: Marriages Between University & Community Radiation Oncology Centers

U.S. Map

New Hanover Regional Medical Center Wilmington University of North Carolina Chapel Hill 160 Miles CDRP in North Carolina

The UNC – NHRMC Bond We started with: Strong foundation Patient referrals (two- way street) Occasional visits CDRP grant added: TELESYNERGY ® New multi-disciplinary & enhanced rad onc relationships Regular tumor boards IMRT shared planning Phase II H&N trial Quarterly visits

A Year of TELESYNERGY ® in NC August 2004 – August 2005 Multi-disciplinary tumor boards 79 Treatment planning 7 Other 9 Total 95

“Improving Cancer Outcomes for African Americans in Southeastern North Carolina”

Rad Onc Clinical Trial Enrollment at NHRMC (2004 – 2006) Disease SiteAfrican American/Total H&N 422 Lung0 6 Breast5 8 Prostate2 2 Cervix0 2 Anal1 2 Total1242

Phase II Trial of Hyperfractionated IMRT with Concurrent Weekly Cisplatin for Stage III & IVa Head & Neck Cancer Designed & opened in community with IMRT planning advice from university Later opened at university A model of cooperation & teamwork!

CDRP Summary Enrollment in adult clinical oncology trials is poor, especially for underserved Relationships b/w university & community cancer centers can be enhanced These bonds may improve patient care, including clinical trial enrollment