Genetic Disorders By: Jenn Moulton, Steph Covey, Ruth Schlegelmilch, Kristin Benson

Genetic Disorders Mutation or variation of genes that leads to a variety of abnormalities 4 main types -Single gene -Multifactorial -Chromosomal -Mitochondrial

2 Types Discussed Single gene -Sickle cell anemia Chromosomal -Down’s Syndrome

Sickle Cell Anemia Incomplete dominant Inherited disorder where abnormal hemoglobin is produced Pain associated with disorder -Chest, arms, legs, fingers and toes Abnormal amount of infections, kidney damage, and eye problems

HH Hh hh

Issues with Sickle Cell Anemia Social -Health problems, social life, Malaria Ethical -Cord blood Political -Having children, health care

Down’s Syndrome Trisomy 21-possess 3 copies chromosome 21 Characteristics -Decreased muscle mass, halo around iris of eye, thickened tongue, Simean creases Risks -Cardiovascular problems, obesity, arthritis, osteoporosis

Issues of Down’s Syndrome Social -Health problems, depression, ear infections Ethical -Abortion Political -Abortion, health care

Summary 4 types of genetic disorders -Single gene, Multifactorial, Chromosomal, Mitochondrial Sickle Cell Anemia -Social, Ethical, Political Down’s Syndrome -Social, Ethical, Political

Thank you! Any questions?