Vision - Part 1 zRight side of your brain controls your Left body functions zLeft side of your brain controls your Right body functions Each eyeball is divided into 2 parts –Right Visual Field –Left Visual Field Right Hemisphere receives visual info from LVF only Left Hemisphere receives visual info from RVF only

Vision - Part 2 z Left Visual Field is illustrated in RED z Right Visual Field is illustrated in BLUE Lesson Outline Split-Brain Discoveries

Ways to study the Brain!!! zAccidents: damage to brain regions can tell us about their functions zPhineas Gage.Phineas Gage

Lesions: tissue destruction Cutting into the brain and looking for change. Brain tumors also lesion brain tissue.

Seizures z3 basic types – Grand Mal Involves total body convulsions, aka “tonic-clonic” – Petit Mal Involves isolated body part convulsion, aka “focal” – Absence Patient becomes unresponsive, and has no memory of occurrence. Appears to be day-dreaming but cannot awake. Very rare.

What is a seizure? 1. Abnormal discharge of electrical impulses within the brain 2. Rather than smooth constant production of Action Potentials, neurons fire without any regulation, causing disruption to brain function at the biochemical level 3.Seizures generally have 3 parts: Aura - period of warning, usually olfactory or visual Ictus - actual seizure period Postictal state - time where body “resets” itself

Causes of Seizures Alcohol Poisoning Drug Overdose/Reaction Head Injury Fever (especially in children) Neurological Defect (usually genetic) Sepsis (in brain) Brain Tumor Stroke Epilepsy Lesson Outline

Epilepsy zA seizure disorder in which reoccurring seizures are the main symptom caused by an abnormal discharge of electrical activity from the neurons in the cerebral cortex. In the US more than 4 million people have some form of epilepsy Risk of epilepsy is greatest in early childhood and late adulthood. Seizures have been found depicted as early as in cavepaintings! 4,000 yr. old writings depict epileptics as “possessed by demons” Julius Caesar, King Charles II, Vincent Van Gogh and novelist Dostoyevsky all reportedly suffered from seizures.

Treatments for Epilepsy z3 major courses of treatment: yDrugs xGenerally first line of attack because it is effective, relatively inexpensive, and safe yDiet xKetogenic diet - lots of fat and almost no carbohydrates xThis diet drastically alters the way our bodies get energy from food - instead of making glucose, it makes ketones ySurgery xCommissurotomy

Commissurotomy zFor patients with frequent and violent epileptic seizures, surgically splitting the corpus callosum was the only relief - known as a “commissurotomy” zCorpus callosum is a bundle of nerve fibers which serve to connect the right and left cerebral hemispheres

Less Invasive ways to study the Brain zElectroencephalogram (EEG) zComputerized Axial Tomography (CAT) zPositron Emission Tomography (PET) zMagnetic Resonance Imaging (MRI) zFunctional MRI

Electroencephalogra m (EEG)  Electrodes placed on the scalp create an amplified recording of the waves of electrical activity that sweep across the brain’s surface

CT scan  CT (computed tomography) Scan  a series of x-ray photographs taken from different angles and combined by computer into a composite representation of a slice through the body; also called CAT scan

PET Scan  PET (positron emission tomography) Scan  a visual display of brain activity that detects where a radioactive form of glucose goes while the brain performs a given task

MRI Scan  MRI (magnetic resonance imaging)  a technique that uses magnetic fields and radio waves to produce computer-generated images that distinguish among different types of soft tissue; allows us to see structures within the brain MRI scan of a healthy individual (left) and a person with schizophrenia (right) Note the enlarged fluid - filled brain region in the image on the right.

fMRI Scan Functional MRI Reveals blood flow, and therefore, brain activity by comparing successive MRI scans. “Reading Your Mind” – 60 Minutes“Reading Your Mind”

Brain Restoration – Plasticity The ability for our brains to form new connections after the neurons are damaged. Evidenced by brain reorganization following damage (especially in children) and in experiments on the effects of experience on brain development The younger you are, the more plastic your brain is. Plasticity of sensory cortex

Brain Restoration  cells in the nervous system that support, nourish, and protect neurons Glial Cells