NIH ROADMAP FOR MEDICAL RESEARCH RESEARCH TEAMS OF THE FUTURE

Research Teams of the Future Goals Encourage Multi- and Inter-disciplinary teams Support larger, coordinated, resource sharing teams Preserve investigator initiated strategy Promote investigators to take creative, unexplored avenues of research

3 High-Risk Research Interdisciplinary Research Private-Public Partnerships Research Teams of the Future

4 NIH Director’s Pioneer Award Criteria: Evidence of scientific innovation and creativity Testimony of intrinsic motivation, enthusiasm and intellectual energy Potential for scientific leadership and evidence of, or potential for, effective communication skills Research Teams of the Future

5 Interdisciplinary Research Planning grants for interdisciplinary research centers (P20 Centers) Innovative training programs Development of methodologies aimed at integrating behavioral and social science into interdisciplinary research Research Teams of the Future

6 P20 Exploratory Centers for Interdisciplinary Research Lower organizational barriers that impede research Enable scientists to conduct research across disciplines Research Teams of the Future

P20 Exploratory Centers Increasing complexity of questions requires multidisciplinary research and interdisciplinary research Combining aspects of individual disciplines to provide new approaches to solving problems Research Teams of the Future

P20 Exploratory Centers—Examples Behavioral Epidemiology  Integrate theoretical methodological and analytic aspects of economic sciences, population sciences, and behavioral sciences to develop a new approach to discovery and intervention in youth vulnerable to HIV/AIDS Imaging Genetics  Draw from genomics, image analysis, statistics, and neuropsychiatry to improve diagnosis and treatment of mental illness and other brain disorders Research Teams of the Future

P20 Exploratory Centers—Examples Antimicrobial resistance  Integrate new disciplines to address the fast growing problem of antimicrobial resistance using novel new strategies developed by interdisciplinary research teams using long-term strategies Obesity research  Integrate disciplines of neuroendocrinology, genetics, and lipid & intermediate metabolism, and clinical epidemiology to better treat and prevent obesity Research Teams of the Future

Interdisciplinary Training Programs New funding mechanisms  Support interdisciplinary work from undergraduate students through postdoctoral researchers Provide foundation for diverse interdisciplinary scientific teams necessary for success of future endeavors Include short and long term:  Training  Curriculum  Methodological development Research Teams of the Future

Interdisciplinary Training Programs- Examples Clinical Research Experience for Engineers  Undergraduate engineers engage in clinical research projects with clinical and bioengineering mentorship, Regenerative Sciences Training Program  Biologists, engineers, and clinicians augment training via didactic and research experiences with focus on musculoskeletal systems Clinical Biodetective Training  Trainees to develop novel methods for detection of disease states, markers of good health, and therapeutic markers Research Teams of the Future

Research at the Interface of the Life and Physical Sciences: Bridging the Sciences Conference Objectives  To identify opportunities at the interface that could result in major advances  To develop approaches to bridge the sciences Co-sponsored by NIH and NSF Held at NIH campus on November 9, 2004  For more information: