Cell Membrane: Structure and Function

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Presentation transcript:

Cell Membrane: Structure and Function

The Plasma Membrane Cell membrane and nuclear membrane are plasma membranes Semi-permeable Phospholipid bilayer with proteins Fluid-mosaic model http://www.susanahalpine.com/anim/Life/memb.htm

Cell Membrane Phospholipid bilayer Two layers = bilayer Lipid Phospho

Why bother with two layers? Water loving (hydrophilic) outside Water fearing (hydrophobic) inside Fears water Loves water Layer 1 Layer 2

Membrane Proteins Channel protein Carrier protein Enzymatic protein Cell recognition protein Enzymatic protein Receptor Protein http://en.wikipedia.org/wiki/File:Fluid_Mosaic.svg

Transport Proteins 1) Channel or 2) Carrier Channel Protein Side View Top down When open allows sugars, salts, and amino acids to pass http://phet.colorado.edu/en/simulation/membrane-channels DOI:10.2210/pdb2jqy/pdb

Carrier Protein Extracellular End Intracellular End Receives a special molecule Opens the closed gate Extracellular End Intracellular End Carrier Protein 10.2210/pdb2bg9/pdb

Channel vs. Carrier Proteins Channel Carrier

3) Cell Recognition Protein What blood type are you? A, B, AB or O? Extracellular DOI:10.2210/pdb2edo/pdb

4) Enzymatic Proteins Angiotensin II Makes a molecule that increases blood pressure

5) Membrane Proteins- Receptor Protein Acetylcholine Receptor Extracellular Intracellular Do you like to move your muscles? 10.2210/pdb2bg9/pdb

Summary Proteins play a large role in the function of cells (therefore our lives) Different types of protein structures have different functions Small examples given there are many thousands of proteins in nature Tutorial/self-check: http://www.bio.davidson.edu/people/macampbell/111/memb-swf/membranes.swf (link on homework page)

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