Chapter 8: Plasticity in the Nervous System. Concept of Plasticity  What does plasticity mean? Guesses?

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Presentation transcript:

Chapter 8: Plasticity in the Nervous System

Concept of Plasticity  What does plasticity mean? Guesses?

1. Closed head injury vs. open head injury 2. Cerebrovascular events (stroke)  There are two types of stroke: a) Ischemia b) Hemorrhage Types of Brain Injury

Cellular ‘events’ Post-Injury 1. Axonal re-growth (not new cell) 2. Sprouting 3. Super-sensitivities –  Disuse  Denervation

How do we Research Brain Injury? 1. Study people with injury 2. Use of animals

Important Factors in Recovery 1. Type & extent of damage 2. Age when injury is sustained

Screw-ups in Recovery 1. Damaged axons can reconnect to the wrong target 2. Phantom Limb

Specific Therapies for CNS Injury 1. Behavioral intervention 2. Rehabilitation 3. Drugs 4. Cell replacement??

Next Time: Exam #1 on Chapters 1-3, 7-8

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