10 November 2008 Finish Ch 12 Cardiovascular Begin Ch 14 Respiratory Physiology Lab this week: Frog heart physiology – Review actions of ACh, Atropine, and EPI – Effects of temperature on HR – Producing heart blocks – Double-pithed Syllabus change: Digestion moved to end

Respiratory Physiology The physics of air flow 1) Flow in tubes 2) Ventilation

Respiration is the overall movement of gases between the outside environment and the internal cells O2O2 O2O2 CO 2 But Carbon Dioxide reacts with water!

The major parts of the “airways,” along which air movements (ventilation) occur during breathing. Upper Respiratory Tract The Structure underlying the function: Lower Respiratory Tract Bronchitis Asthma

Upper Tract Sleep Apnea & CPAP

Continuous Positive Airway Pressure

Larynx

The major parts of the “airways,” along which air movements (ventilation) occur during breathing. Lower Respiratory Tract

Surgical resection

Pulmonary arterial blood = low in O 2

Figure 22.10

The relaxation/contraction of circular smooth muscle lining these “airways’” determines how easily airflow can occur (bronchodilation vs. bronchoconstriction). Most gas exchange occurs in the ~8,000,000 alveolar sacs. Figure 13-2 Anatomical Dead Space

What does a river delta and your lungs have in common?

Figure 13-2 Anatomical Dead Space Impaction Sedimentation Brownian Diffusion Particle Filtration: deposition varies Decrease In Flow Rate

Respiratory Epithelium Mucus escalator

Figure 22.5 Smoker’s hack