Endocrine System. Endocrine glands are composed of cells that secrete: – Hormones amino acid derivatives peptides and proteins steroids.

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Presentation transcript:

Endocrine System

Endocrine glands are composed of cells that secrete: – Hormones amino acid derivatives peptides and proteins steroids

Hormones act by attaching to receptors of specific target cells

Function of endocrine system: – homeostasis – growth and development

Endocrine Glands Hypothalamus – oxytocin production – ADH production – production and secretion of regulatory hormones for anterior pituitary

Pituitary (hypophysis) – posterior pituitary oxytocin secretion ADH secretion

Pituitary (hypophysis) – anterior pituitary Tropic hormones – TSH – ACTH – Gonadotropins: FSH, LH Prolactin Growth hormone

– all anterior pituitary hormones are regulated by hypothalamic hormones – regulation dependent upon hypophyseal portal system

Thyroid Gland

– T 4 and T 3 : released by thyroid follicles – calcitonin: released by C cells

Parathyroid glands

– PTH

Adrenal Gland

– Adrenal cortex mineralocorticoids glucocorticoids adrenal androgens – Adrenal medulla E and NE

Endocrine pancreas – Islets of Langerhans glucagon: from alpha cells insulin: from beta cells somatostatin: from delta cells

Pineal gland – melatonin Heart – ANP Kidney – renin – EPO

Thymus Gland – thymosin

Reproductive System – Testes testosterone inhibin – Ovaries estrogens progesterone

Endocrine Disorders Acromegaly

Endocrine Disorders, continued Acromegaly Gigantism

Endocrine Disorders, continued Acromegaly Gigantism Pituitary Dwarfism

Endocrine Disorders, continued Goiter

Endocrine Disorders, continued Goiter

Endocrine Disorders Grave’s disease

Endocrine Disorders, continued Cretinism

Endocrine Disorders, continued Cushing’s disease

Endocrine Disorders, continued Cushing’s disease Addisons disease

Endocrine Disorders, continued Type I diabetes Type II diabetes

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