Epstein-Barr Virus Brittany Seyler.

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Presentation transcript:

Epstein-Barr Virus Brittany Seyler

What is it? Herpes virus that infects B Cells and Epithelial cells- linked to malignancies in both Responsible for Infectious Mononucleosis 2nd most common

Background Named after M. Anthony Epstein and Yvonne Barr in 1961 Humans are the only known reservoir

Transmission Saliva Blood transfusions Infects 95% of the world’s population 90% of US population infected by age 25

Symptoms Fever Fatigue Sore throat Swollen lymph glands Weight Loss Vomiting Hemolysis

Demographics Occurs worldwide No racial predilection Occurs earlier in females than males

Structure Crystal structure Linear, double stranded DNA “spikes” Viral envelope easily damaged Toroidal shaped core

Representation Of Immuno response vs viral incubation. Each Line Plot represents different antigens to the EBV over the incubation period of the virus as a whole. This scaling can be used in the testing of carriers, and previous carriers of the EBV Representation Of Immuno response vs viral incubation.

Viral Detail Family:Herpesviridae Subfamily:Gammaherpesvirinae Genus:Lymphocryptovirus Species:Human herpesvirus 4 (HHV-4) Associated with several forms of cancer, lymphoma in HIV patients, and believed to be associated with higher risks of autoimmune conditions in those affected.

Prevention

Sources http://www.cdc.gov/ncidod/diseases/ebv.htm http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001617/ http://emedicine.medscape.com/article/963894-overview http://www.pnas.org/content http://www.nature.com/nsmb/journal http://virus.stanford.edu/herpes/transmission.html http://bioweb.uwlax.edu

Thank You :)