Project Overview Jörg Freund, Siemens David Manset, MaatGKnowledge HG09, 29-Jun-09, Berlin

2Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Health-e-Child at a Glance Establish multi-site, vertical, and longitudinal integration of data, information and knowledge Develop a GRID based platform, supported by robust search, optimisation and matching Build enabling tools and services that improve patient care Two main use case scenarios “Aiding the Clinician in Decision Making” “Clinical Studies” Healthy Child Decision Support Systems Integrated Disease Modeling Knowledge Discovery Augment Guidance Guidance Enrich Real-time alert On-line learning Observation Process Sensors Imaging Genomics Lab Data Proteomics Demographics Physician Notes Life Style Time Organ Tissue Cell Molecule Population Individual Vertical Data Integration Integrated Medical Database

3Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Health-e-Child Platform Overview Gateway Grid Grid – EGEE gLite IGGGOSH NECKEROPBG Ontological Layer Query Processing Data Management Cardiology Right Ventricular Overload CardiomyopathyCardiology Right Ventricular Overload CardiomyopathyRheumatology Juvenile Idiopathic ArthritisRheumatology NeuroOncology Brain Tumors / GliomasNeuroOncology Knowledge Discovery Decision Support Systems Disease Models

4Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin 4 paediatric hospitals  4 paediatric hospitals  IGG - Gaslini, Genoa, Italy  GOSH, London, UK  NECKER, Paris, France  OPBG, Rome, Italy  Strong interdisciplinary team  Strong interdisciplinary team across  Countries and languages  Technical and clinical fields  Research on three paediatric areas  Arthritis  Cardiac Disorders  Brain Tumours Health-e-Child Network Year 3 7 technical 7 technical sites 4 clinical 4 clinical sites (1 currently under deployment finalisation)

5Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Overview ICDGALDALMQPE CardiologyCardiologyRheumatologyRheumatologyNeuroOncologyNeuroOncology Auth3D Browser MDMan Heatmap Pat. Browser Data Acq CaseReasoner AITION Treemaps SOFA JIAnnotate CardioViz3D 3DRegTool RADBuilder Automator GridOS

6Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Virtual Physiological Child Decision Support

7Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Knowledge Discovery Virtual Physiological Children

8Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Pediatrics Knowledge Applications

9Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin Demonstration Health-e-Child Demonstrator Integrated Demonstrator Domains Cardiology Rheumatology Oncology Sites Gaslini, Italy Necker, France GOSH, UK Scenarios Personalized Decision support Similarity Search Knowledge Discovery IT Innovation Machine Learning Imaging Data Integration Grid

10Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Collaboration Collaboration (3DKnowl. External Collaborations Network US Network and Collaboration expansion to the US

11Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin

12Health-e-ChildJörg Freund, David Manset, 29 th June 2009, HG09, Berlin EuroNews TV documentary new-frontiers-of-imaging-the-human-body/ new-frontiers-of-imaging-the-human-body/