11 11/16/2015 Filo Viruses Hugh B. Fackrell Filename: Filovir.ppt
22 11/16/2015 Filoviruses Outline l Structure l Classification l Multiplication l Clinical manifestations l Epidemiology l Diagnosis l Control Baron’s Web Site
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44 Ebola virus First photograph 1976
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66 Ebola virus
77 11/16/2015 Ebola virus growing in cell
88 11/16/2015 Marburg Virus
99 11/16/2015 Filovirus l cause disease in humans due to contact with monkeys. l Ebola virus l Book “The Hot Zone” l Movie “Outbreak” l First recognized in Zaire, Kenya, l Zimbabwe 18% have antibodies CDC Fact sheet
10 11/16/2015 Filovirus l Ebola virus l Fever, hemorrhages from multiple sites, diarrhea,vomiting, myalgia, pharyngitis, conjunctivitis, rash. l Patient with all symptoms. 90% death rate l Marburg virus l Lab workers exposed to monkey tissue.7/25 died. l Symptoms same as Ebola. The natural reservoir not identified l Clinical note: pg. 656 Jensen & Wright
11 11/16/2015 DONE!!!