By: Abeer Mohtaseb Najla Bazaya Oraib Horini Supervised by: Dr.Musa Alrefaya.

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Presentation transcript:

By: Abeer Mohtaseb Najla Bazaya Oraib Horini Supervised by: Dr.Musa Alrefaya

Introduction Study Objectives Study Importance Methodology Study Schedule Image De-noising

 The PET image which use to diagnose the cancer disease suffer from noise, this leads to misdiagnosis.

 This research aims to make a comparison between filters which may use in de-noising for PET image to study the effects of the filters to enhance the PET medical image in order to achieve ideal image to detect diseases.

 Helping physicians for better diagnosing patients using PET image.  Decrease the false positive and false negative results.

 Demonstrate qualitative and through simulations.  The validation of the proposed filter employs simulated PET data of a slice of the thorax.  The used methods for comparing the filters results are: PSNR, NR, and correlation.

 Noise: is undesired information that contaminates the image.  De-noising: is the first step to be taken before the images data is analyzed.

1. Gaussian Filter. 2. Wavelet transform. 3. Anisotropic Diffusion Filter. 4. Mean Curvature Motion.

 Perona and Malik Equation: I (t) = div(c (t, x, y) delta I) c (t, x, y) is the edge stopping. x is the gradient magnitude. But when c(t, x, y) = 1..Whats happened??

 Perona has improved it and give an image function g(x): g(x) = 1/1+(x/k)(x/k) Or g(x) = exp((x/k)(x/k)) K:control the sensitivity to edges.

1. Peak Signal-to-Noise Ratio (PSNR): Is the ratio of a signal power to the noise power.

2. Noise Variance (NV): describes the remaining noise level.So, it should be a small as possible.  How will we estimate the noise variance? Noise variance = Variance of the image

Noise fbp Perona & Malik Gaussian Wavelet Curvature PSNR Correleion NV

Noise image Original image Perona Gaussian Curvature Wavelet

Noise osem Perona& Malik Gaussian Wavelet Curvature PSNR Correlation NV

Noise image Original image Perona Gaussian Curvature Wavelet

 PDE-based filters (Perona & Malik and CCM) are the best.

 Our team recommended increasing the number of filters in the comparison process to get the better de-noising result of the PET as possible.

 [1] Goldberg, A, Zwicker, M, Durand, F. Anisotropic Noise. University of California, San Diego MIT CSAIL.  [2] Shidahara, M, Ikomo, Y, Kershaw, J, Kimura, Y, Naganawa, M, Watabe, H. PET kinetic analysis: wavelet denoising of dynamic PET data with application to parametric imaging. Ann Nucl Med –386. (2007).  [3] Greenberg, Sh and Kogan, D. Anisotropic Filtering Techniques applied to Fingerprints. Vision Systems - Segmentation and Pattern Recognition (2007).  [4] Gerig, G, Kubler, O, Kikinis, R and Jolesz, F. A. Nonlinear Anisotropic Filtering of MRI Data. IEEE TRANSACTIONS ON MEDICAL IMAGING. 1(2) (1992).  [5] Olano, M, Mukherjee, Sh and Dorbie, A. Vertex-based Anisotropic Texturing.