Intraosseous Inflammatory Myofibroblastic Tumor of the Twelfth Thoracic Vertebra by Mazda Farshad, Beata Bode, and Kan Min JBJS Case Connect Volume 3(2):e46.

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Intraosseous Inflammatory Myofibroblastic Tumor of the Twelfth Thoracic Vertebra by Mazda Farshad, Beata Bode, and Kan Min JBJS Case Connect Volume 3(2):e46 May 8, 2013 ©2013 by The Journal of Bone and Joint Surgery, Inc.

Fig. 1 Radiograph showing destruction of the right pedicle of T12. Mazda Farshad et al. JBJS Case Connect 2013;3:e46 ©2013 by The Journal of Bone and Joint Surgery, Inc.

Fig. 2 Axial CT of the lesion with a minimal marginal sclerosis. Mazda Farshad et al. JBJS Case Connect 2013;3:e46 ©2013 by The Journal of Bone and Joint Surgery, Inc.

Fig. 3 Core biopsy of the vertebral mass showing spindle cell proliferation with a few mitotic figures (black arrow) and some lymphocytes (white arrows) (hematoxylin and eosin stain, original magnification 100×). Mazda Farshad et al. JBJS Case Connect 2013;3:e46 ©2013 by The Journal of Bone and Joint Surgery, Inc.

Fig. 4 The dural sac is retracted to the left; two straight osteotomes were used for sagittal osteotomy of the vertebral body. Mazda Farshad et al. JBJS Case Connect 2013;3:e46 ©2013 by The Journal of Bone and Joint Surgery, Inc.

An axial-cut section of the resected specimen with tumor mass (white star) (hemorrhagic after the core biopsies) in the pedicle, with infiltration of the vertebral body and costovertebral angle. Mazda Farshad et al. JBJS Case Connect 2013;3:e46 ©2013 by The Journal of Bone and Joint Surgery, Inc.

Figs. 6-A and 6-B Imaging after reconstruction. Mazda Farshad et al. JBJS Case Connect 2013;3:e46 ©2013 by The Journal of Bone and Joint Surgery, Inc.

The resection specimen showed areas of more loosely arranged bland spindle cells with focal collections (stars) of inflammatory cells (lymphocytes and granulocytes) (hematoxylin and eosin stain, original magnification 200×). Mazda Farshad et al. JBJS Case Connect 2013;3:e46 ©2013 by The Journal of Bone and Joint Surgery, Inc.

The FISH technique for the ALK1 gene showed one to two exclusively fused green and red signals in the nuclei of the tumor cells, indicating the lack of the rearrangement of this gene in the tumor tissue. Mazda Farshad et al. JBJS Case Connect 2013;3:e46 ©2013 by The Journal of Bone and Joint Surgery, Inc.