Development of the central nervous system Sanjaya Adikari Department of Anatomy.

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Presentation transcript:

Development of the central nervous system Sanjaya Adikari Department of Anatomy

Neural tube & cavity

1 2 3 Prosencephalon (forebrain) Mesencephalon (midbrain) Rhombencephalon (hindbrain) 1a 2 3a 1b 3b Development of brain

1a 2 3a 1b 3b Telencephalon Cerebral hemispheres Diencephalon Midbrain tectum, tegmentum and cerebral pedunculi Metencephalon pons, upper medulla and cerebellum Myelencephalon lower medulla Thalamus, hypothalamus subthalamus, epithalamus

Lateral ventricle Foramen of Monro Aqueduct 4 th ventricle Central canal of SC 3 rd ventricle

Development of spinal cord and brain stem Mantle layer Marginal layer Neuroepithelial layer

Neuroepithelial cells Gliablast cells Neuroblast cells Neurons Glial cells 1 2 OligodendrogliaAstroglia MicrogliaEpendymal cells

Alar plate (sensory) Basal plate (motor) Sulcus limitans Mantle layer Marginal layer Neuroepithelial layer

Posterior horn Lateral horn Anterior horn Motor Sensory Motor Sensory

BE BA SE VE VA GSA