Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/ HOPE HOsptital Platform for E-health Jean Salzemann Laboratoire de Physique Corpusculaire CNRS/IN2P3 Credits: Paul De Vlieger, Lydia Maigne INFSO-RI

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 2

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 3 Neurosurgery application:  2 sites in Clermont-Ferrand  1 in University of Almeria  1 in Ho Chi Minh City Institute of IT 3 Hope presentation 5/21/2008 Actual use

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 4 Offer a set of different components for medicine purposes.  Don’t give a ready-to-use application Ensure data security and keep privacy.  Crucial in medical world Let the data where they are produced  Typically in hospitals or medical structures Give access and take advantages of grid functionnalities, in terms of storage, computation and communication.  Store medical data on the grid  Perform high CPU consuming calculation 4 Hope presentation 5/21/2008 HOPE: original idea

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 5 What are the field of applications ? – Medical physics  radiotherapy, brachytherapy treatments, nuclear medicine imaging Who will use the platform ? – Physicians – Medical physicists – Researchers What type of data will be used ? – DICOM Medical images  scanner  IRM  SPECT, PET scans – Standard images What type of calculations will be done on the grid ? – Monte Carlo calculations using GATE 5/21/2008 Hope presentation 5 Purpose of our platform

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 6 Server part Client part 6 Hope presentation 5/21/2008 HOPE: Architecture

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 7 5/21/2008 Hope presentation 7 AMGA GRID Other Platform s Communication Calculation Storage Portlets Gridsphere SOAP Tomcat jsp Xml (layout) HOPE ROLES Admin Patient Image Dosimetry AMGA API gLite API WS ManagementService JobService ImageService InformationService MessageService User Informations & rights Images Metadata Patient Information Jobs Status & Management Messages GridUtils MonitoringThreads MDM WISDOM Services Technical description

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 8 Generic Metadata catalog – Metadata management system on the grid – Security management Layer on top of other databases – Common interface – Data base backend independence For our platform: handle “textual” information – Patients sheets – DICOM images metadata 5/21/2008 Hope presentation 8 AMGA

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 9 Management of Medical Images from PACS to the grid – Integration in the next months of MDM (Medical Data Management) from the gLite project:  Direct access of dicom images through the hospital network  Images are available directly by the grid with LFC but stay in the hospital.  Encryption and anonymisation on the fly with gLite-Hydra key server  Rights management with grid certificates 5/21/2008 Hope presentation 9 Hospital medical images access

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 10 Hospital medical images access

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 11 Access for physicians – Smart-card based authentication Hospital medical images – Integration of :  MDM  Hydra  PDM Job management – Use of the WISDOM production environment for a faster and more reliable link to the grid. Add a research-oriented submission of Gate simulations: – Customization of the interface Automatic split in several job the simulation  Optimize the number of jobs to make it as shortest as possible 5/21/2008 Hope presentation 11 Enhancements

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 12 OPHTHALMOLOGIC APPLICATION Medical data management Dosimetric calculation on the grid: Monte-carlo GATE simulation Demonstration

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 13 JOB SUBMISSION Step 1: Choose an image Step 2: Choose a macro Step 3: Launch the calculation on the grid

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 14 JOB STATUS

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 15 JOB RESULTS Generated images of radioactivity diffusion in the eye. To prepare treatments of tumors.

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 16 New application: Regional epidemiology Epidemiology on breast and colon cancer in Auvergne

Enabling Grids for E-sciencE Jean Salzemann EGEE08 Conference – Istanbul – 25/09/08 17 Hope – LifeGrid – EGEE – AMGA – References