Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer.

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Figure 2 The incidence of new onset AF, strokes, heart failure, and mortality according to the BMI (/ person-years). (Left: BMI

Figure 1 Study flow chart

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Figure 1 Mechanism of mortality benefit associated with radial access

Figure 1 A dot plot illustrating the correlation between the yearly absolute risk difference for both MACE and major ... Figure 1 A dot plot illustrating.

Take home figure The protective role of CNP/NPR-B/NPRC.

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Figure 1 Patient selection.

Figure 1 Grant agencies and charitable foundations supporting Plan S.

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Figure 1 ABCDE of primary prevention.2

Presentation transcript:

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors by M. John Chapman, Wilfried Le Goff, Maryse Guerin, and Anatol Kontush EHJ Volume 31(2): January 14, 2010 Published on behalf of the European Society of Cardiology. All rights reserved. © The Author For permissions please

Pathways of reverse cholesterol transport in man. M. John Chapman et al. Eur Heart J 2010;31: Published on behalf of the European Society of Cardiology. All rights reserved. © The Author For permissions please

Comparison of pathways of cholesteryl ester transfer protein-mediated heterotransfer of neutral core lipids between lipoprotein particles in normotriglyceridaemia vs. mixed dyslipidaemia involving moderate to marked hypertriglyceridaemia and subnormal levels of triglyceride- enriched high-density lipoprotein. M. John Chapman et al. Eur Heart J 2010;31: Published on behalf of the European Society of Cardiology. All rights reserved. © The Author For permissions please

Cardiovascular risk remains high despite aggressive statin therapy. M. John Chapman et al. Eur Heart J 2010;31: Published on behalf of the European Society of Cardiology. All rights reserved. © The Author For permissions please